The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit
The Drosophila brain contains a relatively simple circuit for forming Pavlovian associations,
yet it achieves many operations common across memory systems. Recent advances have …
yet it achieves many operations common across memory systems. Recent advances have …
[HTML][HTML] A model for basic emotions using observations of behavior in Drosophila
S Gu, F Wang, NP Patel, JA Bourgeois… - Frontiers in …, 2019 - frontiersin.org
Emotion plays a crucial role, both in general human experience and in psychiatric illnesses.
Despite the importance of emotion, the relative lack of objective methodologies to …
Despite the importance of emotion, the relative lack of objective methodologies to …
The connectome of an insect brain
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
The connectome of the adult Drosophila mushroom body provides insights into function
Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
[PDF][PDF] A genetically encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice
Dopamine (DA) is a central monoamine neurotransmitter involved in many physiological
and pathological processes. A longstanding yet largely unmet goal is to measure DA …
and pathological processes. A longstanding yet largely unmet goal is to measure DA …
[PDF][PDF] A complete electron microscopy volume of the brain of adult Drosophila melanogaster
Drosophila melanogaster has a rich repertoire of innate and learned behaviors. Its 100,000-
neuron brain is a large but tractable target for comprehensive neural circuit mapping. Only …
neuron brain is a large but tractable target for comprehensive neural circuit mapping. Only …
Multisensory learning binds neurons into a cross-modal memory engram
Associating multiple sensory cues with objects and experience is a fundamental brain
process that improves object recognition and memory performance. However, neural …
process that improves object recognition and memory performance. However, neural …
The neuronal architecture of the mushroom body provides a logic for associative learning
We identified the neurons comprising the Drosophila mushroom body (MB), an associative
center in invertebrate brains, and provide a comprehensive map describing their potential …
center in invertebrate brains, and provide a comprehensive map describing their potential …
A connectome of a learning and memory center in the adult Drosophila brain
Understanding memory formation, storage and retrieval requires knowledge of the
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …
Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila
Animals discriminate stimuli, learn their predictive value and use this knowledge to modify
their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes …
their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes …