The centromere is a chromosomal locus that ensures delivery of one copy of each
chromosome to each daughter at cell division. Efforts to understand the nature and …

The centromere is required to ensure the equal distribution of replicated chromosomes to
daughter nuclei. Centromeres are frequently associated with heterochromatin, an enigmatic …

The male-specific region of the Y chromosome, the MSY, differentiates the sexes and
comprises 95% of the chromosome's length. Here, we report that the MSY is a mosaic of …

We have combined long synthetic arrays of alpha satellite DNA with telomeric DNA and
genomic DNA to generate artificial chromosomes in human HT1080 cells. The resulting …

We have identified a new T--> C transition on the human Y chromosome. C-allele
chromosomes have been found only in a subset of the populations from Asia and northern …

We recently described a human marker chromosome containing a functional neo-
centromere that binds anti-centromere antibodies, but is devoid of centromeric α-satellite …

Human centromeres have been extensively studied over the past two decades.
Consequently, more is known of centromere structure and organization in humans than in …

Artificial chromosomes have now become a major research tool in both genome analysis
and in the functional characterization of genes. Yeast artificial chromosomes (YACs)(R. ef. 1; …

Centromeres play a critical role in chromosome inheritance but are among the most difficult
genomic components to analyze in multicellular eukaryotes. Here, we present a highly …

A 745 bp sequence (pSau3A9) located at the centromeres of several cereal species was
isolated from a sorghum BAC library by Jiang et al.(1996, Proc. Natl Acad. Sci. USA, 93 …