Acute pancreatitis is a severe inflammatory disorder with limited treatment options. Improved
understanding of disease mechanisms has led to new and potential therapies. Here we …

Objective Severe acute pancreatitis (SAP), pancreatic inflammation leading to multiorgan
failure, is associated with high morbidity and mortality. There is a critical need to identify …

Pancreatic ductal adenocarcinoma (PDAC) has extensive stromal involvement and remains
one of the cancers with the highest mortality rates. Activin A has been implicated in colon …

Acute Pancreatitis (AP) is associated with high mortality and current treatment options are
limited to supportive care. We found that blockade of activin A (activin) in mice improves …

Purpose Adenocarcinomas of the esophagus (AEG) and stomach (AS) are among the most
common cancers worldwide. Novel markers for risk stratification and guiding treatment are …

METHODS: We assessed whether BMI and serum activin A levels are independent markers
to determine disease severity in a cohort of patients with AP. To evaluate activin A inhibition …

Reflux esophagitis is a result of esophageal exposure to acid and bile during episodes of
gastroesophageal reflux. Aside from chemical injury to the esophageal epithelium, it has …

Background and objective: Portal vein thrombosis is associated with a decrease in the main
blood velocity in this vessel. While most studies examine etiological factors of portal vein …

Purpose: Adenocarcinomas of the esophagus (AEG) and stomach (AS) are among the most
common cancers worldwide. Novel markers for risk stratification and guiding treatment are …

Abstract [eng] In this prospective study, 90 adult participants: 44 patients with mild acute
pancreatitis; 30 patients with chronic pancreatitis; and 16 healthy individuals were examined …