Parkinson disease (PD) is the second most common neurodegenerative disorder, affecting>
1% of the population≥ 65 years of age and with a prevalence set to double by 2030. In …

Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD).
In recent years, research has focused on the pre-dementia stages of cognitive impairment in …

Besides motor symptoms, many individuals with Parkinson's disease develop cognitive
impairment perhaps due to coexisting α-synuclein and Alzheimer's disease pathologies and …

Objective To systematically review and meta-analyse conversion rates from normal
cognition to Mild Cognitive Impairment (MCI) and dementia in Parkinson's disease (PD) …

Mild cognitive impairment (PD-MCI) and dementia (PDD) are among the most frequent non-
motor symptoms in Parkinson's disease (PD). PD-MCI is six times more likely than age …

Background Our understanding of the etiology, pathophysiology, phenotypic diversity, and
progression of Parkinson's disease has stagnated. Consequently, patients do not receive …

Highlights•GPCRs are implicated in the pathophysiology of various neurodegenerative
diseases.•Currently available therapies do not cure the discussed neurodegenerative …

Cognitive impairment is one of the most salient non-motor symptoms of Parkinson disease
(PD) that poses a significant burden on the patients and carers as well as being a risk factor …

The extent to which Alzheimer neuropathology, particularly the accumulation of misfolded
beta-amyloid, contributes to cognitive decline and dementia in Parkinson's disease (PD) is …

Background: Numerous neuropsychological tests and test versions are used in Parkinson's
disease research, but their relative capacity to detect mild cognitive deficits and their …