The pathologies of many infectious, autoimmune and malignant diseases are influenced by
the profiles of cytokine production in pro-inflammatory (TH1) and anti-inflammatory (TH2) T …

Tumor necrosis factor-alpha (TNF-α) is a potent immunomediator and proinflammatory
cytokine that has been implicated in the pathogenesis of a large number of human diseases …

Tumor necrosis factor α (TNFα) is a potent inflammatory cytokine. In human, the TNFα gene
is located within the highly polymorphic major histocompatibility complex (MHC) region on …

Background and aims: Recent studies linked cytokine gene polymorphisms to H pylori
related gastric cancer development. The current study evaluated the role of cytokine gene …

The in vitro study of TNF promoter polymorphism (SNP) function was stimulated by the
numerous case–control (association) studies of the polymorphisms in relation to human …

As more and more polymorphisms are discovered in the genes encoding cytokines, a crucial
question is whether this polymorphism has any functional effect. One of the most widely …

Background & Aims: Polymorphisms that control cytokine production can affect
immunoregulation. The frequency and consequences of these polymorphisms in type 1 …

Currently, there is much interest in the genetic basis for diseases or disease manifestations
and, in particular, in whether they are related to cytokine gene polymorphisms. It has …

The aim of this study was to evaluate the TNFβ Nco I polymorphism (rs909253) and immune-
inflammatory, oxidative, and nitrosative stress (IO&NS) biomarkers as predictors of disease …

Problem Cytokine gene polymorphism studies in women with recurrent spontaneous
abortion (RSA) are reviewed to provide comprehensive understanding and a direction for …