Biomaterials elicit pyroptosis enhancing cancer immunotherapy

MJ Zhang, YY Wang, LL Han, XY Liu… - Advanced Functional …, 2024 - Wiley Online Library
Cancer immunotherapy has the potential to revolutionize the treatment of malignant tumors,
but its effectiveness is limited by the low immune response rate and immune‐related …

Covalent Organic Frameworks: Opportunities for Rational Materials Design in Cancer Therapy

LL Zhou, Q Guan, YB Dong - … Chemie International Edition, 2024 - Wiley Online Library
Nanomedicines are extensively used in cancer therapy. Covalent organic frameworks
(COFs) are crystalline organic porous materials with several benefits for cancer therapy …

Photocatalytic carbon dots‐triggered pyroptosis for whole cancer cell vaccines

Q Cheng, T Zhang, Q Wang, X Wu, L Li… - Advanced …, 2024 - Wiley Online Library
Manufacturing whole cancer cell vaccines (WCCV) with both biosafety and efficacy is crucial
for tumor immunotherapy. Pyroptotic cancer cells, due to their highly immunogenic …

Lithiophilic Covalent Organic Framework as Anode Coating for High‐Performance Lithium Metal Batteries

X Wu, S Zhang, X Xu, F Wen, H Wang… - Angewandte Chemie …, 2024 - Wiley Online Library
The growth of disorganized lithium dendrites and weak solid electrolyte interphase greatly
impede the practical application of lithium metal batteries. Herein, we designed and …

Anthraquinone centers modified covalent organic frameworks for boosted photocatalytic O2-to-H2O2 synthesis: Inhibiting the in-situ decomposition of H2O2

Y Luo, C Liu, J Liu, X Liu, Y Zhou, X Ou, B Weng… - Chemical Engineering …, 2024 - Elsevier
Photocatalytic O 2 reduction presents a sustainable strategy for H 2 O 2 synthesis, while the
in-situ decomposition of H 2 O 2 significantly deteriorates the activity and stability. Here, by …

Controlling the Degree of Interpenetration in Chiral Three-Dimensional Covalent Organic Frameworks via Steric Tuning

K Wang, B Hou, J Dong, H Niu, Y Liu… - Journal of the American …, 2024 - ACS Publications
Network interpenetration plays a crucial role in functionalizing porous framework materials.
However, controlling the degree of interpenetration in covalent organic frameworks (COFs) …

Pyridazine‐Promoted Construction of Vinylene‐Linked Covalent Organic Frameworks with Exceptional Capability of Stepwise Water Harvesting

K Mou, F Meng, Z Zhang, X Li, M Li… - Angewandte Chemie …, 2024 - Wiley Online Library
In this study, we successfully developed two novel vinylene‐linked covalent organic
frameworks (COFs) using 2‐connected 3, 6‐dimethylpyridazine through Knoevenagel …

A Wurster-Type Covalent Organic Framework with Internal Electron Transfer-Enhanced Catalytic Capacity for Tumor Therapy

Y Liu, H Zhao, S Wang, R Niu, S Bi… - Journal of the …, 2024 - ACS Publications
The low immunogenicity of tumors, along with the abnormal structural and biochemical
barriers of tumor-associated vasculature, impedes the infiltration and function of effector T …

Rising interest in the accurate and controllable anticancer strategy: Based on photon-evoked pyroptosis engineering perspective

X Zhang, T Zhang, W Tuo, Y Liu, T Umar… - Coordination Chemistry …, 2024 - Elsevier
Pyroptosis has garnered significant interest due to its involvement in cancer progression and
potential to trigger inflammation and host immune responses. While many efforts have been …

Nanoscale covalent organic framework-mediated pyroelectrocatalytic activation of immunogenic cell death for potent immunotherapy

X Li, ML Gao, SS Wang, Y Hu, D Hou, PN Liu… - Science …, 2024 - science.org
The conventional molecular immunogenic cell death (ICD) inducers suffer from poor
biocompatibility and unsatisfactory efficacy. Here, a biocompatible nanosized covalent …