This review proposes that physical inactivity could be considered a behavior selected by
evolution for resting, and also selected to be reinforcing in life-threatening situations in …

Sex differences in aging occur in many animal species, and they include sex differences in
lifespan, in the onset and progression of age‐associated decline, and in physiological and …

Although physical activity and sedentary behavior are moderately heritable, little is known
about the mechanisms that influence these traits. Combining data for up to 703,901 …

Parkinson's disease (PD) is the second most prevalent late-age onset neurodegenerative
disorder, affecting 1% of the population after the age of about 60 years old and 4% of those …

Williams' evolutionary theory of senescence based on antagonistic pleiotropy has become a
landmark in evolutionary biology, and more recently in biogerontology and evolutionary …

Echoing scientific and industrial progress, the Twentieth century was an unprecedented
period of improvement for human capabilities and performances, with a significant increase …

Natural antioxidants have recently emerged as a highly exciting and significant topic in anti-
aging research. Diverse organism models present a viable protocol for future research …

High-resolution mass spectrometry (HRMS) and nuclear magnetic resonance (NMR)
analysis revealed that there are 20 main components in spores and mycelia extract of …

Background The naked mole-rat (Heterocephalus glaber) is among the most social
mammals on the planet, living in eusocial groups of up to 300 individuals that contain a …

An extensive literature details deterioration of multiple brain functions, especially memory
and learning, during aging in humans and in rodents. In contrast, the decline of social …