The antitumor antibiotics belonging to the tetrahydroisoquinoline family have been studied
thoroughly over the past 25 years starting with the isolation of naphthyridinomycin in 1974 …

1, 3-Dipolar cycloaddition reactions are fundamental processes in organic chemistry, 1 and
their asymmetric version offers a powerful and reliable synthetic methodology to access five …

More Sustainable Approaches for the Synthesis of N-Based Heterocycles | Chemical Reviews
ACS ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS …

This critical review, which is relevant to researchers in synthetic organic chemistry, focuses
on asymmetric 1, 3-dipolar cycloadditions with acrylamides. The use of chiral acrylamides as …

This review will attempt to cover the literatures published from 1988 dealing with cyclic and
acyclic azomethine ylides in which a part or the whole of the ylide conjugation is included in …

The synthesis and biological evaluation of hydrophilic heterobifunctional cross-linkers for
conjugation of antibodies with highly cytotoxic agents are described. These linkers contain …

Tetrahedron report number 442 Disposable Tethers in Synthetic Organic Chemistry Page 1
Pergamon Tetrahedron 54 (1998) 2289-2338 Tetrahedron report number 442 …

AKT and ERK 1/2 play a pivotal role in cancer cell survival, proliferation, migration, and
angiogenesis. Therefore, AKT and ERK 1/2 are considered crucial targets for cancer …

Details of the asymmetric synthesis and complete structure elucidation of (-)-quinocarcin (1),
an antitumor antibiotic that inhibits DNA (and in some systems RNA) synthesis, are reported …

A facile and one-pot synthesis of a series of novel spiropyrrolidines/pyrrolizidines with β-
lactam substituent has been accomplished through 1, 3-dipolar cycloaddition reaction of …