Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

Stroke remains one of the leading causes of long-term disability and mortality despite recent
advances in acute thrombolytic therapies. In fact, the global lifetime risk of stroke in adults …

Although a relationship between traditional cardiovascular risk factors and stroke has long
been recognized, these risk factors likely play a role in other aspects of brain health. Clinical …

Ischemic stroke (IS) is the most prevalent type of stroke. The early diagnosis and prognosis
of IS are crucial for successful therapy and early intervention. Metabolomics, a tool in …

Atherosclerosis is a complex disease, influenced by both genetic and non-genetic factors.
The most important epigenetic mechanism in the pathogenesis of atherosclerosis is DNA …

Introduction Ischemic stroke (IS) is a major contributor to the global disease burden, and
effective biomarkers for IS management in clinical practice are urgently needed …

Metabolomic epidemiology is the high-throughput study of the relationship between
metabolites and health-related traits. This emerging and rapidly growing field has improved …

Background The pathophysiological processes linked to an acute ischemic stroke (IS) can
be reflected in the circulating metabolome. Amino acids (AAs) have been demonstrated to …

Stroke is a major reason for disability and the second highest cause of death in the world.
When a patient is admitted to a hospital, it is necessary to identify the type of stroke, and the …

The time window from stroke onset is critical for the treatment decision. However, in
unknown onset stroke, it is often difficult to determine the exact onset time because of the …