[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Lung MRI with hyperpolarised gases: current & future clinical perspectives

NJ Stewart, LJ Smith, HF Chan… - The British Journal of …, 2022 - academic.oup.com
The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT
remains the gold-standard for structural lung imaging in many clinical indications, technical …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

129Xe and Free‐Breathing 1H Ventilation MRI in Patients With Cystic Fibrosis: A Dual‐Center Study

H Marshall, A Voskrebenzev, LJ Smith… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Free‐breathing 1H ventilation MRI shows promise but only single‐center
validation has yet been performed against methods which directly image lung ventilation in …

[HTML][HTML] The clinical use of lung MRI in cystic fibrosis: what, now, how?

G Dournes, LL Walkup, I Benlala, MM Willmering… - Chest, 2021 - Elsevier
To assess airway and lung parenchymal damage non-invasively in cystic fibrosis (CF), chest
MRI has been historically out of the scope of routine clinical imaging due to technical …

Inter‐and intravisit repeatability of free‐breathing MRI in pediatric cystic fibrosis lung disease

S Munidasa, B Zanette, M Couch… - Magnetic …, 2023 - Wiley Online Library
Purpose The purpose of this study is to assess the intra‐and interscan repeatability of free‐
breathing phase‐resolved functional lung (PREFUL) MRI in stable pediatric cystic fibrosis …

[HTML][HTML] Longitudinal lung function assessment of patients hospitalized with COVID-19 using 1H and 129Xe lung MRI

LC Saunders, GJ Collier, HF Chan, PJC Hughes… - Chest, 2023 - Elsevier
Background Microvascular abnormalities and impaired gas transfer have been observed in
patients with COVID-19. The progression of pulmonary changes in these patients remains …

PhysVENeT: a physiologically-informed deep learning-based framework for the synthesis of 3D hyperpolarized gas MRI ventilation

JR Astley, AM Biancardi, H Marshall, LJ Smith… - Scientific Reports, 2023 - nature.com
Functional lung imaging modalities such as hyperpolarized gas MRI ventilation enable
visualization and quantification of regional lung ventilation; however, these techniques …

Monitoring early stage lung disease in cystic fibrosis

C Nissenbaum, G Davies, A Horsley… - Current Opinion in …, 2020 - journals.lww.com
Monitoring early stage lung disease in cystic fibrosis : Current Opinion in Pulmonary
Medicine Monitoring early stage lung disease in cystic fibrosis : Current Opinion in …

Monitoring and Management of Respiratory Function in Pompe disease: current perspectives

L El Haddad, M Khan, R Soufny, D Mummy… - … and Clinical Risk …, 2023 - Taylor & Francis
Pompe disease (PD) is a neuromuscular disorder caused by a deficiency of acid alpha-
glucosidase (GAA)–a lysosomal enzyme responsible for hydrolyzing glycogen. GAA …