Triple-negative (TNBC) is the most lethal subtype of breast cancer owing to high
heterogeneity, aggressive nature, and lack of treatment options. Chemotherapy remains the …

Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer,
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …

Triple negative breast cancer (TNBC) is most aggressive subtype of breast cancers with high
probability of metastasis as well as lack of specific targets and targeted therapeutics. TNBC …

Ethnopharmacological relevance Triple-negative breast cancer (TNBC) has a poorer
prognosis than other subtypes due to its strong invasion and higher risk of distant …

Signal transducer and activator of transcription 3 (STAT3) is a cytoplasmic transcription
factor that regulates cell proliferation, differentiation, apoptosis, angiogenesis, inflammation …

Abstract Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor
with many important functions in the biology of normal and transformed cells. Its regulation is …

Triple-negative breast cancers (TNBCs) constitute a heterogeneous subtype of breast
cancers that have a poor clinical outcome. Although no approved targeted therapy is …

Simple Summary Trastuzumab is a humanized antibody that has significantly improved the
management and treatment outcomes of patients with cancers that overexpress HER2 …

Triple-negative breast cancer (TNBC) is associated with high recurrence rates, high
incidence of distant metastases, and poor overall survival (OS). Taxane and anthracycline …

The current view is that breast cancer is a stem cell disease characterized by the existence
of cancer cells with stem-like features and tumor-initiating potential. These cells are made …