Background The heart is the central organ of the circulatory system, which maintains the flow
of blood along with the transport of nutrients to different cells and tissues. A well-functioning …

Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

Epidemiological studies have shown that a substantial proportion of acute coronary events
occur in individuals who lack the traditional high-risk cardiovascular (CV) profile. Mental …

Adverse childhood experiences (ACEs) are associated with poor future mental and physical
health. Altered biological reactivity to mental stress may be a possible mechanism linking …

Communication between the brain and peripheral mediators of systemic inflammation is
implicated in numerous psychological, behavioral, and physiological processes. Functional …

What is the function of cognition? On one influential account, cognition evolved to co-
ordinate behaviour with environmental change or complexity (Godfrey-Smith in Complexity …

Social disadvantage and diet composition independently impact myriad dimensions of
health. They are closely entwined, as social disadvantage often yields poor diet quality, and …

Blunted stress reactivity resulting from early exposure to stress during childhood and
adolescence may increase vulnerability to addiction. Early life adversity (ELA) affects brain …

Objective High cardiovascular reactions to psychological stress are associated with the
development of hypertension, systemic atherosclerosis, and cardiovascular disease …

Psychological stress still attracts scientific, clinical, and public interest because of its
suspected connection to health, particularly cardiovascular health. Psychological stress is …