The balance between synthesis and degradation is crucial to maintain cellular homeostasis
and different mechanisms are known to keep this balance. In this review, we will provide a …

The Nomenclature Committee on Cell Death (NCCD, 2009) defines different types of cell
death on the basis of morphological, enzymological, immunological and functional criteria …

The combination of two or more drug is a promising strategy to suppress the multidrug
resistance (MDR) through different action mechanisms. Co-delivery drugs via polymeric …

The β-nitrostyrene family has been shown to suppress cancer cell proliferation and induce
programmed cell death. However, mechanisms underlying β-nitrostyrenes remain less …

Methotrexate (MTX) is commonly used as a standard chemotherapy for many cancers,
however its usage required high doses thereby leading to severe adverse effects. In a trial to …

Background Lung cancer is a fatal disease and a serious health problem worldwide.
Patients are usually diagnosed at an advanced stage, and the effectiveness of …

Many reports have shown that antimicrobial peptides exhibit anticancer abilities. Gomesin
(Gm) exhibits potent cytotoxic activity against cancer cells by a membrane pore formation …

The β-nitrostyrene family have been implicated for anti-cancer property. However, the
pharmacological role of β-nitrostyrene in esophageal cancer remain unclear. Here, a β …

The proteasome inhibitor MLN9708 is an orally administered drug that is hydrolyzed into its
active form, MLN2238 (ixazomib). Compared with Bortezomib, MLN2238 has a shorter …

The β-nitrostyrene family has been shown to suppress cell proliferation and induce
apoptosis in types of various cancers. However, the mechanisms underlying the anticancer …