Sickle cell disease (SCD) is an inherited disorder, which occurs due to a single gene
mutation. It has multisystemic manifestations, affecting millions of people worldwide. The …

Patients with sickle cell disease (SCD) who receive red blood cell (RBC) transfusions have a
higher rate of anti-RBC (allo and auto) antibody development than other transfused subjects …

The incidence of connective tissue diseases such as systemic lupus erythematous (SLE), in
adult patients with sickle cell disease (SCD), appears to be increasing. The exact causes …

Background Patients with sickle cell disease (SCD) present a defective activation of the
alternate complement pathway that increases the risk of infection and is thought to …

Introduction The occurrence of systemic lupus erythematosus has been only rarely reported
in patients with sickle-cell disease. Case presentation We describe the case of a 23-year-old …

This case report describes a rare occurrence of the coexistence of sickle cell disease (SCD)
and systemic lupus erythematosus (SLE) in a 33-year-old female. The overlapping clinical …

Two cases of Afro-Caribbean women with an association of sickle cell disease (SCD) and
systemic lupus erythematosus (SLE) are presented. We discuss the clues to the diagnosis of …

Patients with sickle-cell disease who develop autoimmune connective tissue disorders can
present with similar clinical manifestations and/or complications making them …

Objetivo Relatar um caso de coexistência de lúpus eritematoso sistêmico (LES) e doença
falciforme (DF) com revisão da literatura sobre o tema. Metodologia Relato de caso e …

Introduction. The diagnosis of systemic lupus erythematosus (SLE) in patients with sickle cell
disease (SCD) can be difficult to establish because the musculoskeletal, central nervous …