Computational systems biology
H Kitano - Nature, 2002 - nature.com
To understand complex biological systems requires the integration of experimental and
computational research—in other words a systems biology approach. Computational …
computational research—in other words a systems biology approach. Computational …
OpenWorm: overview and recent advances in integrative biological simulation of Caenorhabditis elegans
The adoption of powerful software tools and computational methods from the software
industry by the scientific research community has resulted in a renewed interest in …
industry by the scientific research community has resulted in a renewed interest in …
Neural circuit policies enabling auditable autonomy
A central goal of artificial intelligence in high-stakes decision-making applications is to
design a single algorithm that simultaneously expresses generalizability by learning …
design a single algorithm that simultaneously expresses generalizability by learning …
Liquid time-constant networks
We introduce a new class of time-continuous recurrent neural network models. Instead of
declaring a learning system's dynamics by implicit nonlinearities, we construct networks of …
declaring a learning system's dynamics by implicit nonlinearities, we construct networks of …
Closed-form continuous-time neural networks
Continuous-time neural networks are a class of machine learning systems that can tackle
representation learning on spatiotemporal decision-making tasks. These models are …
representation learning on spatiotemporal decision-making tasks. These models are …
A complete biomechanical model of Hydra contractile behaviors, from neural drive to muscle to movement
H Wang, J Swore, S Sharma… - Proceedings of the …, 2023 - National Acad Sciences
How does neural activity drive muscles to produce behavior? The recent development of
genetic lines in Hydra that allow complete calcium imaging of both neuronal and muscle …
genetic lines in Hydra that allow complete calcium imaging of both neuronal and muscle …
A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits
We propose a neural information processing system obtained by re-purposing the function
of a biological neural circuit model to govern simulated and real-world control tasks. Inspired …
of a biological neural circuit model to govern simulated and real-world control tasks. Inspired …
Designing worm-inspired neural networks for interpretable robotic control
In this paper, we design novel liquid time-constant recurrent neural networks for robotic
control, inspired by the brain of the nematode, C. elegans. In the worm's nervous system …
control, inspired by the brain of the nematode, C. elegans. In the worm's nervous system …
Learning the dynamics of realistic models of C. elegans nervous system with recurrent neural networks
Given the inherent complexity of the human nervous system, insight into the dynamics of
brain activity can be gained from studying smaller and simpler organisms. While some of the …
brain activity can be gained from studying smaller and simpler organisms. While some of the …
Generalizable machine learning in neuroscience using graph neural networks
Although a number of studies have explored deep learning in neuroscience, the application
of these algorithms to neural systems on a microscopic scale, ie parameters relevant to …
of these algorithms to neural systems on a microscopic scale, ie parameters relevant to …