[HTML][HTML] Molecular mechanisms regulating hair follicle development
SE Millar - Journal of Investigative Dermatology, 2002 - Elsevier
Clinical conditions causing hair loss, such as androgenetic alopecia, alopecia areata, and
scarring alopecia, can be psychologically devastating to individuals and are the target of a …
scarring alopecia, can be psychologically devastating to individuals and are the target of a …
Recent advances in understanding mechanisms of insect cuticle differentiation
B Moussian - Insect biochemistry and molecular biology, 2010 - Elsevier
Insects possess a cuticle that covers all tissues exposed to the outside world including the
body, the fore-and hindgut and the luminal side of the tracheae. The cuticle is a …
body, the fore-and hindgut and the luminal side of the tracheae. The cuticle is a …
Low affinity binding site clusters confer hox specificity and regulatory robustness
In animals, Hox transcription factors define regional identity in distinct anatomical domains.
How Hox genes encode this specificity is a paradox, because different Hox proteins bind …
How Hox genes encode this specificity is a paradox, because different Hox proteins bind …
Phenotypic robustness conferred by apparently redundant transcriptional enhancers
Genes include cis-regulatory regions that contain transcriptional enhancers. Recent reports
have shown that developmental genes often possess multiple discrete enhancer modules …
have shown that developmental genes often possess multiple discrete enhancer modules …
Wnt signaling in osteoblasts and bone diseases
JJ Westendorf, RA Kahler, TM Schroeder - Gene, 2004 - Elsevier
Recent revelations that the canonical Wnt signaling pathway promotes postnatal bone
accrual are major advances in our understanding of skeletal biology and bring tremendous …
accrual are major advances in our understanding of skeletal biology and bring tremendous …
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer
H Roca, J Hernandez, S Weidner, RC McEachin… - PloS one, 2013 - journals.plos.org
Cell plasticity regulated by the balance between the mesenchymal to epithelial transition
(MET) and the opposite program, EMT, is critical in the metastatic cascade. Several …
(MET) and the opposite program, EMT, is critical in the metastatic cascade. Several …
Small Peptides Switch the Transcriptional Activity of Shavenbaby During Drosophila Embryogenesis
A substantial proportion of eukaryotic transcripts are considered to be noncoding RNAs
because they contain only short open reading frames (sORFs). Recent findings suggest …
because they contain only short open reading frames (sORFs). Recent findings suggest …
Diversity of LEF/TCF action in development and disease
L Arce, NN Yokoyama, ML Waterman - Oncogene, 2006 - nature.com
Lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) mediate Wnt signals in the
nucleus by recruiting β-catenin and its co-activators to Wnt response elements (WREs) of …
nucleus by recruiting β-catenin and its co-activators to Wnt response elements (WREs) of …
Wnt/wingless signaling in Drosophila
S Swarup, EM Verheyen - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
The Wingless (Wg) pathway represents one of the best-characterized intercellular signaling
networks. Studies performed in Drosophila over the last 30 years have contributed to our …
networks. Studies performed in Drosophila over the last 30 years have contributed to our …
Morphological evolution through multiple cis-regulatory mutations at a single gene
AP McGregor, V Orgogozo, I Delon, J Zanet… - Nature, 2007 - nature.com
One central, and yet unsolved, question in evolutionary biology is the relationship between
the genetic variants segregating within species and the causes of morphological differences …
the genetic variants segregating within species and the causes of morphological differences …