[HTML][HTML] Impact of the Human Cell Atlas on medicine

JE Rood, A Maartens, A Hupalowska, SA Teichmann… - Nature medicine, 2022 - nature.com
Single-cell atlases promise to provide a 'missing link'between genes, diseases and
therapies. By identifying the specific cell types, states, programs and contexts where disease …

Cardiovascular disease and COVID-19: a consensus paper from the ESC working group on coronary pathophysiology & microcirculation, ESC working group on …

E Cenko, L Badimon, R Bugiardini… - Cardiovascular …, 2021 - academic.oup.com
The cardiovascular system is significantly affected in coronavirus disease-19 (COVID-19).
Microvascular injury, endothelial dysfunction, and thrombosis resulting from viral infection or …

[HTML][HTML] The heterogeneous immune landscape between lung adenocarcinoma and squamous carcinoma revealed by single-cell RNA sequencing

C Wang, Q Yu, T Song, Z Wang, L Song… - … and Targeted Therapy, 2022 - nature.com
A thorough interrogation of the immune landscape is crucial for immunotherapy strategy
selection and prediction of clinical responses in non-small-cell lung cancer (NSCLC) …

[HTML][HTML] COVID-19 and preexisting comorbidities: risks, synergies, and clinical outcomes

B Bigdelou, MR Sepand, S Najafikhoshnoo… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …

[HTML][HTML] Single-cell immunology of SARS-CoV-2 infection

Y Tian, LN Carpp, HER Miller, M Zager… - Nature …, 2022 - nature.com
Gaining a better understanding of the immune cell subsets and molecular factors associated
with protective or pathological immunity against severe acute respiratory syndrome …

Hypertension: do inflammation and immunity hold the key to solving this epidemic?

MS Madhur, F Elijovich, MR Alexander, A Pitzer… - Circulation …, 2021 - Am Heart Assoc
Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

Role of Hypertension on the Severity of COVID-19: A Review

M Peng, J He, Y Xue, X Yang, S Liu… - Journal of …, 2021 - journals.lww.com
The novel coronavirus disease (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has rapidly evolved into a global pandemic. The …

[HTML][HTML] Hypertension and COVID-19: current evidence and perspectives

G Gallo, V Calvez, C Savoia - High Blood Pressure & Cardiovascular …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a real challenge for health …

[HTML][HTML] Intensive care management of patients with COVID-19: a practical approach

LA Hajjar, IBSS Costa, SI Rizk, B Biselli… - Annals of Intensive …, 2021 - Springer
Abstract SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), is
responsible for the largest pandemic facing humanity since the Spanish flu pandemic in the …

[HTML][HTML] Age-specific nasal epithelial responses to SARS-CoV-2 infection

MNJ Woodall, AM Cujba, KB Worlock, KM Case… - Nature …, 2024 - nature.com
Children infected with SARS-CoV-2 rarely progress to respiratory failure. However, the risk
of mortality in infected people over 85 years of age remains high. Here we investigate …