Purpose We summarize the current state of knowledge regarding cell therapy for stress
urinary incontinence and introduce new approaches of using regenerative pharmacology as …

Stress urinary incontinence (SUI) is a significant health concern for patients affected,
impacting their quality of life severely. To investigate mechanisms contributing to SUI …

The leading cause of stress urinary incontinence (SUI) in women is the urethral sphincter
muscle deficiency caused by mechanical stress during pregnancy and vaginal delivery. In …

Background Cell therapy constitutes an attractive alternative to treat stress urinary
incontinence. Although promising results have been demonstrated in this field, the …

Objectives To investigate the therapy of stress urinary incontinence in a preclinical setting
cells were injected into the urethrae of minipigs; however, cells injected by William's needle …

Aim To investigate if injection of cells in the urethral sphincter complex causes unspecific
bulking effects. Methods Human mesenchymal stromal cells were isolated, expanded, and …

Introduction Despite spectacular progress in cellular transplantology, there are still many
concerns about the fate of transplanted cells. More preclinical studies are needed …

Aims The efficacy of cell therapy in patients with stress urinary incontinence (SUI) is lower
than expected. The aim of this study was to determine the injection accuracy rate both with …

Cell therapy is emerging as an alternative treatment of stress urinary incontinence. However,
many aspects of the procedure require further optimization. A large animal model is needed …

Muscular insufficiency is observed in many conditions after injury, chronic inflammation, and
especially in elderly populations. Causative cell therapies for muscle deficiencies are not …