MicroRNAs and complex diseases: from experimental results to computational models
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …
viruses and animals. As one of the most important components in the cell, miRNAs play a …
Dissecting miRNA signature in colorectal cancer progression and metastasis
X Huang, X Zhu, Y Yu, W Zhu, L Jin, X Zhang, S Li… - Cancer letters, 2021 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer
related deaths worldwide. Despite recent advancements in surgical and molecular targeted …
related deaths worldwide. Despite recent advancements in surgical and molecular targeted …
Gefitinib versus placebo in completely resected non–small-cell lung cancer: results of the NCIC CTG BR19 study
Purpose Survival of patients with completely resected non–small-cell lung cancer (NSCLC)
is unsatisfactory, and in 2002, the benefit of adjuvant chemotherapy was not established …
is unsatisfactory, and in 2002, the benefit of adjuvant chemotherapy was not established …
[HTML][HTML] Exosome-transmitted miRNA-335-5p promotes colorectal cancer invasion and metastasis by facilitating EMT via targeting RASA1
X Sun, F Lin, W Sun, W Zhu, D Fang, L Luo, S Li… - … Therapy-Nucleic Acids, 2021 - cell.com
Exosomal microRNA (miRNA) secretion has been characterized as a vital factor in
intercellular communication among cancer cells. However, little is known about cancer …
intercellular communication among cancer cells. However, little is known about cancer …
[HTML][HTML] Roles of the canonical myomiRs miR-1,-133 and-206 in cell development and disease
KR Mitchelson, WY Qin - World journal of biological chemistry, 2015 - ncbi.nlm.nih.gov
MicroRNAs are small non-coding RNAs that participate in different biological processes,
providing subtle combinational regulation of cellular pathways, often by regulating …
providing subtle combinational regulation of cellular pathways, often by regulating …
[HTML][HTML] The fundamental role of miR-10b in metastatic cancer
P Sheedy, Z Medarova - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
Small, non-coding strands of RNA have been identified as a significant player in the
pathology of cancer. One of the first miRNAs to be shown as having aberrant expression in …
pathology of cancer. One of the first miRNAs to be shown as having aberrant expression in …
pH-responsive DNA hydrogels with ratiometric fluorescence for accurate detection of miRNA-21
S Yao, L Xiang, L Wang, H Gong, F Chen, C Cai - Analytica Chimica Acta, 2022 - Elsevier
DNA hydrogels are powerful candidates for stable and sensitive detection of disease-related
nucleic acids. However, the ability to accurately detect is the cornerstone of disease …
nucleic acids. However, the ability to accurately detect is the cornerstone of disease …
[HTML][HTML] Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
JB Kjersem, T Ikdahl, OC Lingjaerde, T Guren… - Molecular …, 2014 - Elsevier
The conventional first-line chemotherapy for metastatic colorectal cancer (mCRC) consists of
fluorouracil (5-FU) in combination with either oxaliplatin or irinotecan. We have explored …
fluorouracil (5-FU) in combination with either oxaliplatin or irinotecan. We have explored …
The prognostic value of microRNAs varies with patient race/ethnicity and stage of colorectal cancer
LC Bovell, C Shanmugam, BDK Putcha… - Clinical cancer …, 2013 - AACR
Purpose: MicroRNAs (miRNA) have potential prognostic value for colorectal cancers;
however, their value based on patient race/ethnicity and pathologic stage has not been …
however, their value based on patient race/ethnicity and pathologic stage has not been …
[PDF][PDF] The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment
P Tokarz, J Blasiak - Acta Biochimica Polonica, 2012 - bibliotekanauki.pl
microRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression
by targeting specific mRNAs. microRNAs play a role in several physiological processes in …
by targeting specific mRNAs. microRNAs play a role in several physiological processes in …