Soft structures are capable of undergoing reversible large strains and deformations when
facing different types of loadings. Due to the limitations of linear elastic models, researchers …

Aortic stiffness increases markedly with age and is associated with excess risk for various
adverse clinical outcomes, including heart disease, dementia, and kidney disease. Although …

The mechanical properties of human aortas are linked to the layered tissue and its
microstructure at different length scales. Each layer has specific mechanical and structural …

Vascular ageing, characterized by structural and functional changes in blood vessels of
which arterial stiffness and endothelial dysfunction are key components, is associated with …

Aortic dissection continues to be responsible for significant morbidity and mortality, although
recent advances in medical data assimilation and in experimental and in silico models have …

Experiments were carried out on 15 human descending thoracic aortas from heart-beating
healthy donors who donated organs for transplant. The aortas were kept refrigerated in …

Elastic and muscular arteries differ in structure, function, and mechanical properties, and
may adapt differently to aging. We compared the descending thoracic aortas (TA) and the …

Cardiovascular diseases are the leading cause of death worldwide and include, among
others, critical conditions of the aortic wall. Importantly, such critical conditions require …

Experimental data and a suitable material model for human aortas with smooth muscle
activation are not available in the literature despite the need for developing advanced grafts; …

Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …