Background: Searching for new cytotoxic agents with apoptosis induction may represent a
viable strategy for cancer treatment to overcome the increased resistance to available …

Coumarin and its nitrogen analogue 1-aza coumarin are a class of lactones and lactams,
respectively, which are indispensable heterocyclic units to both chemists and biochemists. 1 …

A series of imidazolin‐2‐thione derivatives was synthesized and structurally confirmed
through the use of different spectroscopic techniques such as infrared, nuclear magnetic …

Aim: To synthesize new hybrid cinnamic acids (10a, 10b and 11) and ester derivatives (7, 8
and 9) and investigate their anti-breast cancer activities. Materials & methods: Compounds 7 …

Background: Hybridization of coumarin moiety with additional antitumor pharmacophores is
an auspicious stratagem to afford precious therapeutic interference for the medication of …

Aims: In this study, novel synthesized 1, 6-disubstituted-1-azacoumarin-3-carboxylic acid
derivatives were designed, synthesized and evaluated as potential anticancer agents …

A series of coumarin and aza-coumarin derivatives (II–IX) were synthesized and identified
using IR, 1H NMR, and 13C NMR spectral data. All the synthesized compounds were …

Background The influenza virus is a highly contagious respiratory disease that causes
seasonal outbreaks and occasionally, unpredictable pandemics with high morbidity and …

A series of new ethyl 7-hydroxy-2-oxo-1, 2-dihydroquinoline-3-carboxylates and their
halogenated derivatives were synthesized. Ethyl 7-hydroxy-2-oxo-1, 2-dihydroquinoline-3 …