Bioengineering approaches to treat the failing heart: from cell biology to 3D printing

M Yadid, H Oved, E Silberman, T Dvir - Nature Reviews Cardiology, 2022 - nature.com
Successfully engineering a functional, human, myocardial pump would represent a
therapeutic alternative for the millions of patients with end-stage heart disease and provide …

Inverse opal scaffolds and their biomedical applications

YS Zhang, C Zhu, Y Xia - Advanced Materials, 2017 - Wiley Online Library
Three‐dimensional porous scaffolds play a pivotal role in tissue engineering and
regenerative medicine by functioning as biomimetic substrates to manipulate cellular …

[HTML][HTML] Glycosaminoglycan-based biomaterials for growth factor and cytokine delivery: Making the right choices

D Hachim, TE Whittaker, H Kim, MM Stevens - Journal of controlled release, 2019 - Elsevier
Controlled, localized drug delivery is a long-standing goal of medical research, realization of
which could reduce the harmful side-effects of drugs and allow more effective treatment of …

Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors

Y Brudno, AB Ennett-Shepard, RR Chen, M Aizenberg… - Biomaterials, 2013 - Elsevier
Therapeutic stimulation of angiogenesis to re-establish blood flow in ischemic tissues offers
great promise as a treatment for patients suffering from cardiovascular disease or trauma …

Sequential delivery of angiogenic growth factors improves revascularization and heart function after myocardial infarction

HK Awada, NR Johnson, Y Wang - Journal of controlled release, 2015 - Elsevier
Abstract Treatment of ischemia through therapeutic angiogenesis faces significant
challenges. Growth factor (GF)-based therapies can be more effective when concerns such …

Therapeutic angiogenesis: controlled delivery of angiogenic factors

H Chu, Y Wang - Therapeutic delivery, 2012 - Future Science
Therapeutic angiogenesis aims at treating ischemic diseases by generating new blood
vessels from existing vasculature. It relies on delivery of exogenous factors to stimulate …

Spheroids as vascularization units: From angiogenesis research to tissue engineering applications

MW Laschke, MD Menger - Biotechnology advances, 2017 - Elsevier
Multi-cellular spheroids mimic the complex three-dimensional environment of natural
tissues. Accordingly, they are also used as vascularization units in angiogenesis research …

[HTML][HTML] Urine-derived stem cells for potential use in bladder repair

D Qin, T Long, J Deng, Y Zhang - Stem cell research & therapy, 2014 - Springer
Engineered bladder tissues, created with autologous bladder cells seeded on
biodegradable scaffolds, are being developed for use in patients who need cystoplasty …

Platelet-derived growth factor-coated decellularized meniscus scaffold for integrative healing of meniscus tears

KI Lee, M Olmer, J Baek, DD D'Lima, MK Lotz - Acta biomaterialia, 2018 - Elsevier
The aim of this study was to examine the potential of platelet-derived growth factor (PDGF)-
coated decellularized meniscus scaffold in mediating integrative healing of meniscus tears …

Collagen/heparin scaffold combined with vascular endothelial growth factor promotes the repair of neurological function in rats with traumatic brain injury

J Zhang, X Liu, K Ma, M Chen, H Xu, X Niu, H Gu… - Biomaterials …, 2021 - pubs.rsc.org
The objective of this study was to evaluate the therapy effects of a novel biological scaffold
containing heparin, collagen and vascular endothelial growth factor (VEGF) in treating …