Epilepsy and cannabidiol: a guide to treatment

A Arzimanoglou, U Brandl, JH Cross… - Epileptic …, 2020 - Wiley Online Library
The growing interest in cannabidiol (CBD), specifically a pure form of CBD, as a treatment
for epilepsy, among other conditions, is reflected in recent changes in legislation in some …

Pharmacological and therapeutic properties of cannabidiol for epilepsy

V Franco, E Perucca - Drugs, 2019 - Springer
Cannabidiol (CBD) is a major active component of the Cannabis plant, which, unlike
tetrahydrocannabinol (THC), is devoid of euphoria-inducing properties. During the last 10 …

Cannabidiol as a potential treatment for psychosis

C Davies, S Bhattacharyya - Therapeutic advances in …, 2019 - journals.sagepub.com
Psychotic disorders such as schizophrenia are heterogeneous and often debilitating
conditions that contribute substantially to the global burden of disease. The introduction of …

Neuropharmacological effects of the main phytocannabinoids: a narrative review

RG Dos Santos, JEC Hallak, JAS Crippa - … and neuropsychiatric disorders, 2021 - Springer
Cannabis can synthetize more than 400 compounds, including terpenes, flavonoids, and
more than 100 phytocannabinoids. The main phytocannabinoids are Δ-9 …

Pharmacokinetics of oral and intravenous cannabidiol and its antidepressant-like effects in chronic mild stress mouse model

C Xu, T Chang, Y Du, C Yu, X Tan, X Li - Environmental Toxicology and …, 2019 - Elsevier
Cannabidiol (CBD) exhibits significant efficacy in mental and inflammatory diseases.
Several studies have recently reported on the rapid antidepressant-like effects of CBD …

Palmitoylethanolamide: A potential alternative to cannabidiol

P Clayton, S Subah, R Venkatesh, M Hill… - Journal of Dietary …, 2023 - Taylor & Francis
The endocannabinoid system (ECS) is a widespread cell signaling network that maintains
homeostasis in response to endogenous and exogenous stressors. This has made the ECS …

[HTML][HTML] Oral cannabidiol prevents allodynia and neurological dysfunctions in a mouse model of mild traumatic brain injury

C Belardo, M Iannotta, S Boccella, F Ricciardi… - Frontiers in …, 2019 - frontiersin.org
Neurological dysfunctions are the most impactful and persistent consequences of traumatic
brain injury (TBI). Indeed, previous reports suggest that an association between TBI and …

[HTML][HTML] Medical cannabis in children

A Aran, D Cayam-Rand - Rambam Maimonides medical journal, 2020 - ncbi.nlm.nih.gov
The use of medical cannabis in children is rapidly growing. While robust evidence currently
exists only for pure cannabidiol (CBD) to treat specific types of refractory epilepsy, in most …

Lipid-based molecules on signaling pathways in autism spectrum disorder

K Yui, G Imataka, S Yoshihara - International Journal of Molecular …, 2022 - mdpi.com
The signaling pathways associated with lipid metabolism contribute to the pathophysiology
of autism spectrum disorder (ASD) and provide insights for devising new therapeutic …

Cognitive and behavioral effects of cannabidiol in patients with treatment-resistant epilepsy

B Metternich, K Wagner, MJ Geiger, M Hirsch… - Epilepsy & Behavior, 2021 - Elsevier
Purpose Therapeutic use of cannabidiol (CBD) in intractable epilepsies has increased
considerably over the last ten years. As more evidence for the potentially beneficial effects of …