[HTML][HTML] Prospective clinical biomarkers of caspase-mediated apoptosis associated with neuronal and neurovascular damage following stroke and other severe brain …
OY Glushakova, AA Glushakov, DS Wijesinghe… - Brain …, 2017 - journals.lww.com
Acute brain injuries, including ischemic and hemorrhagic stroke, as well as traumatic brain
injury (TBI), are major worldwide health concerns with very limited options for effective …
injury (TBI), are major worldwide health concerns with very limited options for effective …
Redox proteomics and the dynamic molecular landscape of the aging brain
M Perluigi, AM Swomley, DA Butterfield - Ageing research reviews, 2014 - Elsevier
It is well established that the risk to develop neurodegenerative disorders increases with
chronological aging. Accumulating studies contributed to characterize the age-dependent …
chronological aging. Accumulating studies contributed to characterize the age-dependent …
[HTML][HTML] Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling
Our bodies are in constant motion and so are the neurons that invade each tissue. Motion-
induced neuron deformation and damage are associated with several neurodegenerative …
induced neuron deformation and damage are associated with several neurodegenerative …
Role of caspase-3-mediated apoptosis in chronic caspase-3-cleaved tau accumulation and blood–brain barrier damage in the corpus callosum after traumatic brain …
OY Glushakova, AO Glushakov… - Journal of …, 2018 - liebertpub.com
Traumatic brain injury (TBI) may be a significant risk factor for development of
neurodegenerative disorders such as chronic traumatic encephalopathy (CTE), post …
neurodegenerative disorders such as chronic traumatic encephalopathy (CTE), post …
Cerebellar ataxias: β‐III spectrin's interactions suggest common pathogenic pathways
E Perkins, D Suminaite, M Jackson - The Journal of physiology, 2016 - Wiley Online Library
Spinocerebellar ataxias (SCAs) are a genetically heterogeneous group of disorders all
characterised by postural abnormalities, motor deficits and cerebellar degeneration. Animal …
characterised by postural abnormalities, motor deficits and cerebellar degeneration. Animal …
Cerebrospinal fluid protein biomarker panel for assessment of neurotoxicity induced by kainic acid in rats
OY Glushakova, A Jeromin, J Martinez… - Toxicological …, 2012 - academic.oup.com
Glutamate excitotoxicity plays a key role in the etiology of a variety of neurological,
psychiatric, and neurodegenerative disorders. The goal of this study was to investigate …
psychiatric, and neurodegenerative disorders. The goal of this study was to investigate …
[HTML][HTML] GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects
HH Park, HS Kwon, KY Lee, YE Kim, JW Son… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
GV1001, which mimics the activity of human telomerase reverse transcriptase, protects
neural cells from amyloid beta (Aβ) toxicity and other stressors through extra-telomeric …
neural cells from amyloid beta (Aβ) toxicity and other stressors through extra-telomeric …
[图书][B] Biomarkers of brain injury and neurological disorders
KKW Wang, Z Zhang, FH Kobeissy - 2014 - books.google.com
This book explores the recent advances in the techniques and platforms used in biomarker
research that have revolutionized the way we study, diagnose, and treat brain injury …
research that have revolutionized the way we study, diagnose, and treat brain injury …
iTRAQ-based proteomic analysis of APPSw, Ind mice provides insights into the early changes in Alzheimer's disease
N Li, P Hu, T Xu, H Chen, X Chen, J Hu… - Current Alzheimer …, 2017 - ingentaconnect.com
Background: Several proteins have been identified as potential diagnostic biomarkers in
imaging, genetic, or proteomic studies in Alzheimer disease (AD) patients and mouse …
imaging, genetic, or proteomic studies in Alzheimer disease (AD) patients and mouse …
Age-related intraneuronal accumulation of αII-spectrin breakdown product SBDP120 in the human cerebrum is enhanced in Alzheimer's disease
HX Zhu, ZQ Xue, WY Qiu, ZJ Zeng, JP Dai, C Ma… - Experimental …, 2015 - Elsevier
Spectrins are a part of cytoskeletal platform that lines the intracellular side of plasma
membrane, which can be proteolyzed by calcium-sensitive enzymes including calpains and …
membrane, which can be proteolyzed by calcium-sensitive enzymes including calpains and …