Role of Lactobacillus reuteri in Human Health and Diseases

Q Mu, VJ Tavella, XM Luo - Frontiers in microbiology, 2018 - frontiersin.org
Lactobacillus reuteri (L. reuteri) is a well-studied probiotic bacterium that can colonize a
large number of mammals. In humans, L. reuteri is found in different body sites, including the …

Biofilm Forming Lactobacillus: New Challenges for the Development of Probiotics

MJ Salas-Jara, A Ilabaca, M Vega, A García - Microorganisms, 2016 - mdpi.com
Probiotics are live bacteria, generally administered in food, conferring beneficial effects to
the host because they help to prevent or treat diseases, the majority of which are …

Promising therapeutic strategies against microbial biofilm challenges

K Zhang, X Li, C Yu, Y Wang - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Biofilms are communities of microorganisms that are attached to a biological or abiotic
surface and are surrounded by a self-produced extracellular matrix. Cells within a biofilm …

Nanotechnology in combating biofilm: A smart and promising therapeutic strategy

YK Mohanta, I Chakrabartty, AK Mishra… - Frontiers in …, 2023 - frontiersin.org
Since the birth of civilization, people have recognized that infectious microbes cause serious
and often fatal diseases in humans. One of the most dangerous characteristics of …

Probiotic mechanisms of action

K Halloran, MA Underwood - Early human development, 2019 - Elsevier
Intestinal dysbiosis is associated with a large number of disease processes including
necrotizing enterocolitis and late-onset sepsis in preterm infants and colic and antibiotic …

Current research on the epidemiology, pathogenesis, and management of necrotizing enterocolitis

S Eaton, CM Rees, NJ Hall - Neonatology, 2017 - karger.com
Despite decades of research on necrotizing enterocolitis, we still do not fully understand the
pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of …

Results of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder

LM Schmitt, EG Smith, EV Pedapati, PS Horn, M Will… - Scientific Reports, 2023 - nature.com
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized
by core impairments in social communication as well as restricted, repetitive patterns of …

Next-generation probiotic therapy to protect the intestines from injury

MV Ragan, SJ Wala, SD Goodman… - Frontiers in Cellular …, 2022 - frontiersin.org
Probiotics are live microorganisms that, when administered in adequate amounts, provide
health benefits to the host. Some strains of the probiotic Lactobacillus reuteri (L. reuteri) …

Antibacterial and anti-inflammatory effects of Lactobacillus reuteri in its biofilm state contribute to its beneficial effects in a rat model of experimental necrotizing …

RD Shelby, P Mar, GE Janzow… - Journal of Pediatric …, 2022 - Elsevier
Introduction Necrotizing enterocolitis (NEC) remains a significant surgical emergency in
neonates. We have demonstrated the efficacy of Lactobacillus reuteri (Lr) in protecting …

An enhanced Lactobacillus reuteri biofilm formulation that increases protection against experimental necrotizing enterocolitis

JK Olson, JB Navarro, JM Allen… - American Journal …, 2018 - journals.physiology.org
One significant drawback of current probiotic therapy for the prevention of necrotizing
enterocolitis (NEC) is the need for at least daily administration because of poor probiotic …