Emerging perspectives of synaptic biomarkers in ALS and FTD

K Krishnamurthy, RK Pradhan - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are debilitating
neurodegenerative diseases with shared pathological features like transactive response …

[HTML][HTML] Early deficits in GABA inhibition parallels an increase in L-type Ca2+ currents in the jaw motor neurons of SOD1G93A mouse model for ALS

S Venugopal, Z Ghulam-Jelani, IS Ahn, X Yang… - Neurobiology of …, 2023 - Elsevier
Abstract Amyotrophic Lateral Sclerosis (ALS) involves protracted pre-symptomatic periods of
abnormal motor neuron (MN) excitability occurring in parallel with central and peripheral …

[PDF][PDF] Current Methods In ALS Research

YE Klingl, S Da Cruz… - Jove-Journal Of …, 2023 - researchgate.net
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects
roughly 1 in 400 people in their lifetime. The disease initially presents as upper and lower …

Diminished GAD67 Terminals and Ambient GABA Inhibition Associated with Reduced Motor Neuron Recruitment Threshold in the SOD1G93A ALS mouse

S Venugopal, Z Ghulam-Jhelani, D Simmons… - bioRxiv, 2021 - biorxiv.org
Pre-symptomatic studies in mouse models of the neurodegenerative motor neuron (MN)
disease, Amyotrophic Lateral Sclerosis (ALS) highlight early alterations in intrinsic and …

Emerging perspectives of synaptic biomarkers in ALS and FTD

K Krishnamurthy, RK Pradhan - europepmc.org
Abstract Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are
debilitating neurodegenerative diseases with shared pathological features like transactive …