FGF21 agonists: an emerging therapeutic for metabolic dysfunction-associated steatohepatitis and beyond
SA Harrison, T Rolph, M Knott, J Dubourg - Journal of Hepatology, 2024 - Elsevier
The worldwide epidemics of obesity, hypertriglyceridemia, dyslipidaemia, type 2 diabetes,
and metabolic dysfunction-associated steatotic liver disease (MASLD)/metabolic dysfunction …
and metabolic dysfunction-associated steatotic liver disease (MASLD)/metabolic dysfunction …
Erythropoietin mitigated thioacetamide-induced renal injury via JAK2/STAT5 and AMPK pathway
The kidney flushes out toxic substances and metabolic waste products, and homeostasis is
maintained owing to the kidney efforts. Unfortunately, kidney disease is one of the illnesses …
maintained owing to the kidney efforts. Unfortunately, kidney disease is one of the illnesses …
SIRT1/Nrf2/NF-κB signaling mediates anti-inflammatory and anti-apoptotic activities of oleanolic acid in a mouse model of acute hepatorenal damage
Background and objectives: Oleanolic acid (OA) is a penta-cyclic triterpene with diverse
bioactivities such as anticarcinogenic, antiviral, antimicrobial, hepatoprotective, anti …
bioactivities such as anticarcinogenic, antiviral, antimicrobial, hepatoprotective, anti …
Preparation and characterization of blank and nerolidol-loaded chitosan–alginate nanoparticles
Recently, there has been a growing interest in using natural products as treatment
alternatives in several diseases. Nerolidol is a natural product which has been shown to …
alternatives in several diseases. Nerolidol is a natural product which has been shown to …
The Effect of Nerolidol Renal Dysfunction following Ischemia–Reperfusion Injury in the Rat
Efforts to decrease the deleterious effects of renal ischemia–reperfusion injury (IRI) are
ongoing. Recently, there has been increasing interest in using natural phytochemical …
ongoing. Recently, there has been increasing interest in using natural phytochemical …
Renoprotective Effect of Pitavastatin against TAA‐Induced Renal Injury: Involvement of the miR‐93/PTEN/AKT/mTOR Pathway
MA Elbaset, BMSA Mohamed… - Advances in …, 2024 - Wiley Online Library
This research investigated if pitavastatin (Pita) might protect rats' kidneys against
thioacetamide (TAA). By altering the PTEN/AKT/mTOR pathway, pitavastatin may boost …
thioacetamide (TAA). By altering the PTEN/AKT/mTOR pathway, pitavastatin may boost …
[HTML][HTML] Unveiling the Potential of Silymarin, Spirulina platensis, and Chlorella vulgaris towards Cardiotoxicity via Modulating Antioxidant Activity, Inflammation, and …
HF El-Gendy, HK Khalifa, A Omran, RMS Korany… - Life, 2024 - mdpi.com
This study assessed the possible pharmacological effects of Chlorella vulgaris (Cg),
Spirulina platensis (St), and silymarin (Sl) against thioacetamide (TA)-induced cardiotoxicity …
Spirulina platensis (St), and silymarin (Sl) against thioacetamide (TA)-induced cardiotoxicity …
[HTML][HTML] The ameliorating role of sofosbuvir and daclatasvir on thioacetamide-induced kidney injury in adult albino rats
AH Moustafa, HF Pasha, MA Abas… - Anatomy & Cell …, 2023 - synapse.koreamed.org
Thioacetamide (TAA) exposure and hepatitis C virus infection are usually associated with
renal dysfunction. Sofosbuvir (SFV) and daclatasvir (DAC) drugs combination has great …
renal dysfunction. Sofosbuvir (SFV) and daclatasvir (DAC) drugs combination has great …
[HTML][HTML] Curcumin alleviates thioacetamide-induced kidney toxicity in rats: enhancing antioxidant system, and attenuating oxidative stress, DNA damage, and …
Abstract Thioacetamide (TAA), well-known as a toxic agent and has been reported to be
nephrotoxic due to oxidative stress induction and proinflammatory markers increase …
nephrotoxic due to oxidative stress induction and proinflammatory markers increase …
Olmutinib Reverses Thioacetamide-Induced Cell Cycle Gene Alterations in Mice Liver and Kidney Tissues, While Wheat Germ Treatment Exhibits Limited Efficacy at …
Background and Objectives: TAA is potent hepatic/renal toxicant. Conversely, WGO is a
potent dietary supplement with impressive antioxidant properties. Olmutinib is an apoptotic …
potent dietary supplement with impressive antioxidant properties. Olmutinib is an apoptotic …