Disease-associated regulation of gene expression by resveratrol: Special focus on the PI3K/AKT signaling pathway
S Ghafouri-Fard, Z Bahroudi, H Shoorei… - Cancer Cell …, 2022 - Springer
Abstract Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) is a natural phenol that is present in
the skin of the grape, blueberry, raspberry, mulberry, and peanut. This substance is …
the skin of the grape, blueberry, raspberry, mulberry, and peanut. This substance is …
Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis
KE Hostettler, J Zhong, E Papakonstantinou… - Respiratory …, 2014 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor
prognosis. The kinase inhibitor nintedanib specific for vascular endothelial growth factor …
prognosis. The kinase inhibitor nintedanib specific for vascular endothelial growth factor …
Close teamwork between Nrf2 and peroxiredoxins 1 and 6 for the regulation of prostaglandin D2 and E2 production in macrophages in acute inflammation
T Ishii - Free Radical Biology and Medicine, 2015 - Elsevier
Inflammation is a complex biological self-defense reaction triggered by tissue damage or
infection by pathogens. Acute inflammation is regulated by the time-and cell type-dependent …
infection by pathogens. Acute inflammation is regulated by the time-and cell type-dependent …
In vitro and in vivo evaluation of anti-arthritic, antioxidant efficacy of fucoidan from Undaria pinnatifida (Harvey) Suringar
Seaweed and their constituents have been traditionally employed for the management of
various human pathologic conditions such as edema, urinary disorders and inflammatory …
various human pathologic conditions such as edema, urinary disorders and inflammatory …
Mechanism research on a bioactive resveratrol–PLA–gelatin porous nano-scaffold in promoting the repair of cartilage defect
F Yu, M Li, Z Yuan, F Rao, X Fang, B Jiang… - International journal …, 2018 - Taylor & Francis
Background Articular cartilage defects are difficult to treat, but drug-loaded tissue
engineering scaffolds provide a possible treatment option for these types of injuries …
engineering scaffolds provide a possible treatment option for these types of injuries …
Taurocholate induces cyclooxygenase-2 expression via the sphingosine 1-phosphate receptor 2 in a human cholangiocarcinoma cell line
R Liu, X Li, X Qiang, L Luo, PB Hylemon, Z Jiang… - Journal of Biological …, 2015 - ASBMB
Cholangiocarcinoma (CCA) is a rare, but highly malignant primary hepatobiliary cancer with
a very poor prognosis and limited treatment options. Our recent studies reported that …
a very poor prognosis and limited treatment options. Our recent studies reported that …
Metals-triggered compound CDPDP exhibits anti-arthritic behavior by downregulating the inflammatory cytokines, and modulating the oxidative storm in mice models …
SS Hassan, SQ Abbas, I Muhammad, JJ Wu… - Frontiers in …, 2022 - frontiersin.org
Triggering through abiotic stress, including chemical triggers like heavy metals, is a new
technique for drug discovery. In this research, the effect of heavy metal Nickel on …
technique for drug discovery. In this research, the effect of heavy metal Nickel on …
[HTML][HTML] The thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and …
SM Yu, SJ Kim - International journal of molecular …, 2015 - spandidos-publications.com
Dedifferentiation and inflammation are major features of cartilage degeneration during the
pathogenesis of osteoarthritis (OA). Thymoquinone (TQ) is the major compound of black …
pathogenesis of osteoarthritis (OA). Thymoquinone (TQ) is the major compound of black …
[HTML][HTML] Resveratrol inhibits the IL-1β-induced expression of MMP-13 and IL-6 in human articular chondrocytes via TLR4/MyD88-dependent and-independent …
H Gu, Y Jiao, X Yu, X Li, W Wang… - … journal of molecular …, 2017 - spandidos-publications.com
The natural polyphenolic compound, resveratrol, has been shown to exhibit anti-
osteoarthritic activity. Therefore it is hypothesized that resveratrol may serve as a nutritional …
osteoarthritic activity. Therefore it is hypothesized that resveratrol may serve as a nutritional …
Effects of resveratrol on collagen type II protein in the superficial and middle zone chondrocytes of porcine articular cartilage
M Maepa, M Razwinani, S Motaung - Journal of ethnopharmacology, 2016 - Elsevier
Ethnopharmacological relevance Resveratrol (RSV) was first isolated in 1940 from the roots
of white hellebore (Veratrum grandiflorum (Maxim. ex Miq) O. Loes) and in 1963 from the …
of white hellebore (Veratrum grandiflorum (Maxim. ex Miq) O. Loes) and in 1963 from the …