The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease

LA Díaz, JP Arab, A Louvet, R Bataller… - Nature Reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

Novel insights into metabolic‐associated steatotic liver disease preclinical models

R Montero‐Vallejo, D Maya‐Miles, J Ampuero… - Liver …, 2024 - Wiley Online Library
Metabolic‐associated steatotic liver disease (MASLD) encompasses a wide spectrum of
metabolic conditions associated with an excess of fat accumulation in the liver, ranging from …

A Western diet with alcohol in drinking water recapitulates features of alcohol‐associated liver disease in mice

M Schonfeld, M O'Neil, MT Villar… - Alcoholism: Clinical …, 2021 - Wiley Online Library
Background Mouse models of alcohol‐associated liver disease vary greatly in their ease of
implementation and the pathology they produce. Effects range from steatosis and mild …

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol

A Lamas-Paz, M Mesquita, M Garcia-Lacarte… - Frontiers in …, 2024 - frontiersin.org
Background Alcohol misuse, binge drinking pattern, and gender-specific effects in the
middle-aged population has been clearly underestimated. In the present study, we focused …

[HTML][HTML] Effects of moderate alcohol consumption in non-alcoholic fatty liver disease

P Lemmer, P Manka, J Best, A Kahraman… - Journal of Clinical …, 2022 - mdpi.com
Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) have emerged
as leading causes of chronic liver diseases worldwide. ALD and NAFLD share several …

[HTML][HTML] Loss of Cdkn1a protects against MASLD alone or with alcohol intake by preserving lipid homeostasis

A Lamas-Paz, A Hionides-Gutiérrez, F Guo, G Jorquera… - JHEP Reports, 2024 - Elsevier
Abstract Background & Aim Expression of P21, encoded by the CDKN1A gene, has been
associated with fibrosis progression in steatotic liver disease (SLD); however, the underlying …

Role of EpCAM+ CD133+ extracellular vesicles in steatosis to steatohepatitis transition in NAFLD

R Muñoz‐Hernández, S Gato, A Gil‐Gómez… - Liver …, 2023 - Wiley Online Library
Abstract Background and Aims Extracellular vesicles (EVs) have emerged as a potential
source of circulating biomarkers in liver disease. We evaluated circulating AV+ EpCAM+ …

[HTML][HTML] Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational …

R Gallego-Durán, A Albillos, J Ampuero… - … y Hepatología (English …, 2022 - Elsevier
This is a meeting report of the 3rd Translational Hepatology Meeting held in Alicante, Spain,
in October 2021. The meeting, which was organized by the Spanish Association for the …

[HTML][HTML] A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis

M Babuta, C Morel, M de Carvalho Ribeiro… - Hepatology …, 2024 - journals.lww.com
Background: The recent increase in the incidence of alcohol-associated hepatitis (AH)
coincides with the obesity epidemic in the United States. However, current mouse models do …

[HTML][HTML] Alcohol-induced epigenetic changes prevent fibrosis resolution after alcohol cessation in miceresolution

M Schonfeld, M O'Neil, SA Weinman, I Tikhanovich - Hepatology, 2024 - journals.lww.com
Hepatology AASLD Publications Hepatology Liver Transplantation Clinical Liver Disease
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