Current estimates suggest that nearly half a billion people worldwide are affected by hearing
loss. Because of the major psychological, social, economic, and health ramifications …

Non-coding RNAs (ncRNAs) play a critical role in the entire body, and their mis-regulation is
often associated with disease. In parallel with the advances in high-throughput sequencing …

The regulatory mechanisms of circadian rhythms have been studied primarily at the level of
the transcription–translation feedback loops of protein-coding genes. Regulatory modules …

Background Progressive hearing loss is a common problem in the human population with
no effective therapeutics currently available. However, it has a strong genetic contribution …

Abstract Purpose The conserved miR-183/96/182 cluster (miR-183C) regulates both corneal
sensory innervation and corneal resident immune cells (CRICs). This study is to uncover its …

Background The molecular complexity of neural retina development remains poorly studied.
Knowledge of retinal neurogenesis regulation sheds light on retinal degeneration therapy …

Circadian rhythm regulates physiological cycles of awareness and sleepiness. Melatonin
production is primarily regulated by circadian regulation of gene expression and is involved …

Accumulating evidence on the role of non-protein-coding RNA sequences in the regulation
of gene expression is greatly expanding our understanding of the flow of genetic information …

Cells in the human retina must rapidly adapt to constantly changing visual stimuli. This fast
adaptation to varying levels and wavelengths of light helps to regulate circadian rhythms …

Abstract The microRNA (miR)-183/96/182 cluster plays important roles in the development
and functions of sensory organs, including the inner ear. Point-mutations in the seed …