Setting up and sustaining blood and marrow transplant services for children in middle-income economies: an experience-driven position paper on behalf of the EBMT …

L Faulkner, M Verna, A Rovelli, RK Agarwal… - Bone Marrow …, 2021 - nature.com
Severe blood disorders and cancer are the leading cause of death and disability from
noncommunicable diseases in the global pediatric population and a major financial burden …

Prevention programmes and prenatal diagnosis for beta thalassemia in Pakistan: A narrative review

M Ghafoor, MF Sabar, F Sabir - Journal of Pakistan Medical …, 2021 - go.gale.com
Beta Thalassemia is the most prevalent autosomal recessive genetic disorder that results
from errors in beta ([beta]) globin gene and ultimately reduced synthesis of [beta]-Globin …

Recommendations on hematopoietic stem cell transplantation for patients with Diamond–Blackfan anemia. On behalf of the Pediatric Diseases and Severe Aplastic …

C Diaz-de-Heredia, D Bresters, L Faulkner… - Bone Marrow …, 2021 - nature.com
Diamond Blackfan anemia (DBA) is a rare congenital syndrome presenting primarily as pure
red cell aplasia with constitutional abnormalities and cancer predisposition. Established …

Life expectancy and risk factors for early death in patients with severe thalassemia syndromes in South India

R Dhanya, A Sedai, K Ankita, L Parmar… - Blood …, 2020 - ashpublications.org
In spite of advances in chelation therapy and screening of blood, mortality associated with
the most common life-threatening noncommunicable disease of children in India, transfusion …

Immune recovery after in vivo T‐cell depletion myeloablative conditioning hematopoietic stem cell transplantation in severe beta‐thalassemia children

F Qin, L Shi, Q Li, Z Zhang, L Liu, J Li… - European Journal of …, 2019 - Wiley Online Library
Background The clinical outcome of hematopoietic stem cell transplantation (HSCT) in those
with severe beta‐thalassemia (β‐TM) is closely related to post‐transplantation immune …

[HTML][HTML] The case for high resolution extended 6-loci HLA typing for identifying related donors in the Indian subcontinent

RK Agarwal, A Kumari, A Sedai, L Parmar… - Biology of Blood and …, 2017 - Elsevier
Three-loci low-resolution (LR) or intermediate-resolution HLA typing is generally considered
adequate in the related blood and marrow transplantation (BMT) context. However, a single …

Hematopoietic stem cell transplantation in patients with hemoglobinopathies

MA Yesilipek - Hemoglobin, 2020 - Taylor & Francis
Hemoglobinopathies are the most common single-gene diseases and are estimated to affect
millions of people worldwide. Thalassemia and sickle cell disease are the most prevalent …

Finding a balance in reduced toxicity hematopoietic stem cell transplantation for thalassemia: role of infused CD3+ cell count and immunosuppression

B Meissner, P Lang, P Bader, M Hoenig… - Bone Marrow …, 2024 - nature.com
We performed a retrospective analysis on 124 patients with transfusion-dependent
thalassemia who were registered in the German pediatric registry for stem cell …

Haploidentical transplant for paediatric patients with severe thalassaemia using post‐transplant cyclophosphamide and methotrexate: A prospectively registered …

J Hu, S Gong, K Chen, R Yang, L Wang… - British Journal of …, 2023 - Wiley Online Library
Haploidentical transplantation strategies for patients with transfusion‐dependent
thalassaemia (TD‐TM) remain to be investigated. In this study, 54 paediatric patients with TD …

Challenges in managing graft-versus-host disease in developing countries: a perspective

MS Saleem, M Aljurf, A Srivastava, T Shamsi… - Bone Marrow …, 2019 - nature.com
Hematopoietic cell transplant (HCT) activity is increasing worldwide due to safer techniques,
widening indications, and more availability of donors. New HCT centers have recently been …