Sleep disturbances after general anesthesia: current perspectives

M Luo, B Song, J Zhu - Frontiers in neurology, 2020 - frontiersin.org
The purpose of this article is to review (1) sleep mechanism under general anesthesia,
harmful effects of postoperative sleep disturbances;(2) risk factors associated with …

Parenteral ready-to-use fixed-dose combinations including NSAIDs with paracetamol or metamizole for multimodal analgesia—approved products and challenges

F Silva, G Costa, F Veiga, C Cardoso… - Pharmaceuticals, 2023 - mdpi.com
The combination of non-steroidal anti-inflammatory drugs (NSAIDs) with non-opioid
analgesics is common in clinical practice for the treatment of acute painful conditions like …

DDX3 modulates cisplatin resistance in OSCC through ALKBH5-mediated m6A-demethylation of FOXM1 and NANOG

O Shriwas, M Priyadarshini, SK Samal, R Rath… - Apoptosis, 2020 - Springer
Platinum based drugs alone or in combination with 5FU and docetaxel are common regimen
chemotherapeutics for the treatment of advanced OSCC. Chemoresistance is one of the …

Ocular bioanalysis of moxifloxacin and ketorolac tromethamine in rabbit lacrimal matrix using liquid chromatography–tandem mass spectrometry

AC Bisen, RS Bhatta - Bioanalysis, 2024 - Taylor & Francis
Aim: The fixed-dose combination of moxifloxacin (MOXI) and ketorolac tromethamine (KTR)
is widely used for the treatment of bacterial keratitis. Thus, a new LC–MS/MS method was …

Fever integrates antimicrobial defences, inflammation control, and tissue repair in a cold-blooded vertebrate

F Haddad, AM Soliman, ME Wong, EH Albers… - Elife, 2023 - elifesciences.org
Multiple lines of evidence support the value of moderate fever to host survival, but the
mechanisms involved remain unclear. This is difficult to establish in warm-blooded animal …

[HTML][HTML] Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations

EM Del Amo, A Hammid, M Tausch… - International Journal of …, 2022 - Elsevier
Quantitation of ocular drug metabolism is important, but only sparse data is currently
available. Herein, the pharmacokinetics of four drugs, substrates of metabolizing enzymes …

Topical delivery of ketorolac tromethamine via cataplasm for inflammatory pain therapy

Z Hou, Q Wen, W Zhou, P Yan, H Zhang, J Ding - Pharmaceutics, 2023 - mdpi.com
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used in the treatment of
inflammatory pain, such as in osteoarthritis. Ketorolac tromethamine is considered to be an …

Tanezumab: therapy targeting nerve growth factor in pain pathogenesis

MK Patel, AD Kaye, RD Urman - Journal of Anaesthesiology …, 2018 - journals.lww.com
In recent years, nerve growth factor (NGF) and the NGF receptor have become potential
therapeutic targets in the treatment of acute and chronic pain states. NGF is a neurotrophin …

Bioinspired Carbon Dots-Based Fluorescent Sensor for the Selective Determination of a Potent Anti-Inflammatory Drug in the Presence of Its Photodegradation …

M Rizk, E Ramzy, S Toubar, AM Mahmoud… - ACS …, 2024 - ACS Publications
Herein, we synthesized biogenic carbon dots (CDs) with blue-shifted maximum excitation
(λex/λem of 320/404 nm) from largely wasted tangerine seeds for the first time via a one-step …

Comparison of intravenous ketorolac at three doses for treating renal colic in the emergency department: A noninferiority randomized controlled trial

L Eidinejad, M Bahreini, A Ahmadi… - Academic …, 2021 - Wiley Online Library
Background Ketorolac tromethamine is a nonsteroidal anti‐inflammatory drug (NSAID) that
is extensively used for the management of renal colic in the emergency department (ED). It …