Methodologies for bacterial ribonuclease characterization using RNA-seq

L Broglia, A Le Rhun… - FEMS microbiology …, 2023 - academic.oup.com
Bacteria adjust gene expression at the post-transcriptional level through an intricate network
of small regulatory RNAs and RNA-binding proteins, including ribonucleases (RNases) …

Polyribonucleotide nucleotidyltransferase 1 participates in metabolic-associated fatty liver disease pathogenesis by affecting lipid metabolism and mitochondrial …

C Guan, X Zou, C Yang, W Shi, J Gao, Y Ge, Z Xu… - Molecular …, 2024 - Elsevier
Objective Metabolic-associated fatty liver disease (MAFLD) represents one of the most
prevalent chronic liver conditions worldwide, but its precise pathogenesis remains unclear …

The five homologous CiaR-controlled Ccn sRNAs of Streptococcus pneumoniae modulate Zn-resistance

NR De Lay, N Verma, D Sinha, A Garrett… - PLoS …, 2024 - journals.plos.org
Zinc is a vital transition metal for all bacteria; however, elevated intracellular free Zn levels
can result in mis-metalation of Mn-dependent enzymes. For Mn-centric bacteria such as …

Long-term evolution of Streptococcus mitis and Streptococcus pneumoniae leads to higher genetic diversity within rather than between human populations

C Davison, S Tallman, M de Ste-Croix, M Antonio… - PLoS …, 2024 - journals.plos.org
Evaluation of the apportionment of genetic diversity of human bacterial commensals within
and between human populations is an important step in the characterization of their …

The absence of PNPase activity in Enterococcus faecalis results in alterations of the bacterial cell-wall but induces high proteolytic and adhesion activities

R Ladjouzi, M Duban, A Lucau-Danila, D Drider - Gene, 2022 - Elsevier
Enterococci are lactic acid bacteria (LAB) used as starters and probiotics, delineating their
positive attributes. Nevertheless, enterococci can be culprit for thousands of infectious …

[HTML][HTML] RNase R Affects the Level of Fatty Acid Biosynthesis Transcripts Leading to Changes in membrane Fluidity

AF Alípio, C Bárria, V Pobre, AR Matos, SC Prata… - Journal of Molecular …, 2024 - Elsevier
Previous studies on RNase R have highlighted significant effects of this ribonuclease in
several processes of Streptococcus pneumoniae biology. In this work we show that …

The Pneumococcal Protein SufC Binds to Host Plasminogen and Promotes Its Conversion into Plasmin

Y Yasui, S Hirayama, T Hiyoshi, T Isono, H Domon… - Microorganisms, 2023 - mdpi.com
Streptococcus pneumoniae causes otitis media, sinusitis, and serious diseases such as
pneumonia and bacteremia. However, the in vivo dynamics of S. pneumoniae infections and …

A Small Non-Coding RNA Modulates Expression of Pilus-1 Type in Streptococcus pneumoniae

P Acebo, C Herranz, LB Espenberger, A Gómez-Sanz… - Microorganisms, 2021 - mdpi.com
Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide, and about
30% of the pneumococcal clinical isolates show type I pili-like structures. These long …

RNase R, a New Virulence Determinant of Streptococcus pneumoniae

C Bárria, D Mil-Homens, SN Pinto, AM Fialho… - Microorganisms, 2022 - mdpi.com
Pneumococcal infections have increasingly high mortality rates despite the availability of
vaccines and antibiotics. Therefore, the identification of new virulence determinants and the …

RNase R Controls Membrane Fatty Acid Composition in Streptococcus pneumoniae

A Filipe Alípio, C Bárria, V Pobre, R Matos, M Amblar… - bioRxiv, 2023 - biorxiv.org
Previous studies on RNase R have highlighted significant effects of this ribonuclease in
several processes of Streptococcus pneumoniae biology. In this work we have studied the …