[HTML][HTML] An overview of substrate stiffness guided cellular response and its applications in tissue regeneration

B Yi, Q Xu, W Liu - Bioactive materials, 2022 - Elsevier
Cell-matrix interactions play a critical role in tissue repair and regeneration. With gradual
uncovering of substrate mechanical characteristics that can affect cell-matrix interactions …

Hydrogel bioink reinforcement for additive manufacturing: a focused review of emerging strategies

D Chimene, R Kaunas, AK Gaharwar - Advanced materials, 2020 - Wiley Online Library
Bioprinting is an emerging approach for fabricating cell‐laden 3D scaffolds via robotic
deposition of cells and biomaterials into custom shapes and patterns to replicate complex …

Enhancement of therapeutic potential of mesenchymal stem cell-derived extracellular vesicles

KS Park, E Bandeira, GV Shelke, C Lässer… - Stem cell research & …, 2019 - Springer
After the initial investigations into applications of mesenchymal stem cells (MSCs) for cell
therapy, there was increased interest in their secreted soluble factors. Following studies of …

Tissue stiffness dictates development, homeostasis, and disease progression

AM Handorf, Y Zhou, MA Halanski, WJ Li - Organogenesis, 2015 - Taylor & Francis
Tissue development is orchestrated by the coordinated activities of both chemical and
physical regulators. While much attention has been given to the role that chemical regulators …

[HTML][HTML] Advances and challenges in stem cell culture

C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …

Nanoengineered osteoinductive bioink for 3D bioprinting bone tissue

D Chimene, L Miller, LM Cross… - … applied materials & …, 2020 - ACS Publications
Bioprinting is an emerging additive manufacturing approach to the fabrication of patient-
specific, implantable three-dimensional (3D) constructs for regenerative medicine. However …

Three-dimensional piezoelectric fibrous scaffolds selectively promote mesenchymal stem cell differentiation

SM Damaraju, Y Shen, E Elele, B Khusid… - Biomaterials, 2017 - Elsevier
The discovery of electric fields in biological tissues has led to efforts in developing
technologies utilizing electrical stimulation for therapeutic applications. Native tissues, such …

[HTML][HTML] Bioactive polymeric materials and electrical stimulation strategies for musculoskeletal tissue repair and regeneration

B Ferrigno, R Bordett, N Duraisamy, J Moskow… - Bioactive materials, 2020 - Elsevier
Electrical stimulation (ES) is predominantly used as a physical therapy modality to promote
tissue healing and functional recovery. Research efforts in both laboratory and clinical …

Epitranscriptomic modifications in mesenchymal stem cell differentiation: advances, mechanistic insights, and beyond

J Zheng, Y Lu, Y Lin, S Si, B Guo, X Zhao… - Cell Death & …, 2024 - nature.com
RNA modifications, known as the “epitranscriptome”, represent a key layer of regulation that
influences a wide array of biological processes in mesenchymal stem cells (MSCs). These …

Intrinsic mechanical cues and their impact on stem cells and embryogenesis

J Petzold, E Gentleman - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Although understanding how soluble cues direct cellular processes revolutionised the study
of cell biology in the second half of the 20th century, over the last two decades, new insights …