Evolving role of diet in the pathogenesis and treatment of inflammatory bowel diseases

A Levine, RS Boneh, E Wine - Gut, 2018 - gut.bmj.com
Recent advances in basic and clinical science over the last 3 years have dramatically
altered our appreciation of the role of diet in inflammatory bowel diseases (IBD). The marked …

Not all fibers are born equal; variable response to dietary fiber subtypes in IBD

H Armstrong, I Mander, Z Zhang, D Armstrong… - Frontiers in …, 2021 - frontiersin.org
Diet provides a safe and attractive alternative to available treatment options in a variety of
diseases; however, research has only just begun to elucidate the role of diet in chronic …

The P2X7 Receptor Mediates Toxoplasma gondii Control in Macrophages through Canonical NLRP3 Inflammasome Activation and Reactive Oxygen Species …

ACA Moreira-Souza, CLC Almeida-da-Silva… - Frontiers in …, 2017 - frontiersin.org
Toxoplasma gondii (T. gondii) is the protozoan parasite that causes toxoplasmosis, a
potentially fatal disease to immunocompromised patients, and which affects approximately …

Nucleic acid sensing in mammals and plants: facts and caveats

M Heil, I Vega-Muñoz - International review of cell and molecular biology, 2019 - Elsevier
The accumulation of nucleic acids in aberrant compartments is a signal of danger: fragments
of cytosolic or extracellular self-DNA indicate cellular dysfunctions or disruption, whereas …

Nigericin promotes NLRP3-independent bacterial killing in macrophages

H Armstrong, M Bording-Jorgensen, R Chan… - Frontiers in …, 2019 - frontiersin.org
Altered microbiota has been associated with a number of diseases, including inflammatory
bowel diseases, diabetes, and cancer. This dysregulation is thought to relate the host …

Seminal bacterioflora of two rooster lines: Characterization, antibiotic resistance patterns and possible impact on semen quality

E Tvrdá, M Petrovičová, F Benko, M Ďuračka, J Kováč… - Antibiotics, 2023 - mdpi.com
This study aimed to characterize the bacterial profiles and their association with selected
semen quality traits among two chicken breeds. Thirty Lohmann Brown and thirty ROSS 308 …

[HTML][HTML] Novel functional role of heat shock protein 90 in mitochondrial connexin 43-mediated hypoxic postconditioning

RH Tu, QJ Li, Z Huang, Y He, JJ Meng… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Previous studies have shown that heat shock protein 90 (HSP90)-
mediated mitochondrial import of connexin 43 (Cx43) is critical in preconditioning …

Critical Role for the NLRP3 Inflammasome in Mediating IL-1β Production in Shigella sonnei-Infected Macrophages

LH Li, TL Chen, HW Chiu, CH Hsu, CC Wang… - Frontiers in …, 2020 - frontiersin.org
Shigella is one of the leading bacterial causes of diarrhea worldwide, affecting more than
165 million people annually. Among the serotypes of Shigella, Shigella sonnei is …

Macrophages and epithelial cells mutually interact through NLRP3 to clear infection and enhance the gastrointestinal barrier

M Bording-Jorgensen, H Armstrong, M Wickenberg… - Immuno, 2021 - mdpi.com
Activation of the nod-like receptor protein 3 (NLRP3) leads to the release of the
proinflammatory cytokine IL-1β, which then facilitates pathogen control by macrophages …

Attaching and effacing pathogens modulate host mitochondrial structure and function

A Harishankar, VK Viswanathan - … Review of Cell and Molecular Biology, 2023 - Elsevier
Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) are human
enteric pathogens that contribute significantly to morbidity and mortality worldwide. These …