Biological activity of ionic liquids and their application in pharmaceutics and medicine
KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …
modern science. Because of their highly tunable nature and exceptional properties, ionic …
Ionic liquids as a potential tool for drug delivery systems
N Adawiyah, M Moniruzzaman, S Hawatulaila… - …, 2016 - pubs.rsc.org
The pharmaceutical industries face a series of challenges in the delivery of many newly
developed drug molecules because of their low solubility, bioavailability, stability and …
developed drug molecules because of their low solubility, bioavailability, stability and …
Do Ionic Liquids Exhibit the Required Characteristics to Dissolve, Extract, Stabilize, and Purify Proteins? Past-Present-Future Assessment
Proteins are highly labile molecules, thus requiring the presence of appropriate solvents and
excipients in their liquid milieu to keep their stability and biological activity. In this field, ionic …
excipients in their liquid milieu to keep their stability and biological activity. In this field, ionic …
Active pharmaceutical ingredient poly (ionic liquid)-based microneedles for the treatment of skin acne infection
T Zhang, B Sun, J Guo, M Wang, H Cui, H Mao… - Acta Biomaterialia, 2020 - Elsevier
As an inflammatory skin disease of pilosebaceous follicles, Propionibacterium acnes (P.
acnes) can aggravate local inflammatory responses and forms acne lesions. However, due …
acnes) can aggravate local inflammatory responses and forms acne lesions. However, due …
Liquid formulations based on ionic liquids in biomedicine
WX Zhang, YR Gao, R Xue, W Nguyen, W Chen… - Materials Today …, 2023 - Elsevier
Ionic liquids (ILs) are innovative ionic solvents with unique properties of negligible vapor
pressure, favorable conductivity, high thermal and chemical stability as well as self …
pressure, favorable conductivity, high thermal and chemical stability as well as self …
Antibacterial, anti-inflammatory and wet-adhesive poly (ionic liquid)-based oral patch for the treatment of oral ulcers with bacterial infection
Z Zhang, Q Zhang, S Gao, H Xu, J Guo, F Yan - Acta biomaterialia, 2023 - Elsevier
Oral aphthous ulcers are a common inflammatory efflorescence of oral mucosa, presenting
as inflammation and oral mucosal damage and manifesting as pain. The moist and highly …
as inflammation and oral mucosal damage and manifesting as pain. The moist and highly …
'Pro et contra'ionic liquid drugs–Challenges and opportunities for pharmaceutical translation
A Balk, U Holzgrabe, L Meinel - European Journal of Pharmaceutics and …, 2015 - Elsevier
Ionic liquids (ILs) are organic salts with a melting point below 100° C. Active pharmaceutical
ingredients (APIs) are transformed into ILs by combining them with typically large yet …
ingredients (APIs) are transformed into ILs by combining them with typically large yet …
Pharmaceutical applications of lidocaine-based ionic liquids–a remarkable innovation in drug delivery
Over the last few decades, there has been a growing interest in developing innovative drug
delivery approaches that can assist drug release to attain the vital extent of therapeutic …
delivery approaches that can assist drug release to attain the vital extent of therapeutic …
Ionic liquids in drug delivery
Definition Ionic liquids (ILs) are molten salts composed of a large organic cation and an
organic/inorganic anion. Due to their ionic character, most ILs present advantageous …
organic/inorganic anion. Due to their ionic character, most ILs present advantageous …
Cytotoxic activity of salicylic acid-containing drug models with ionic and covalent binding
KS Egorova, MM Seitkalieva… - ACS Medicinal …, 2015 - ACS Publications
Three different types of drug delivery platforms based on imidazolium ionic liquids (ILs) were
synthesized in high preparative yields, namely, the models involving (i) ionic binding of drug …
synthesized in high preparative yields, namely, the models involving (i) ionic binding of drug …