Establishing outcome measures in early knee osteoarthritis

CA Emery, JL Whittaker, A Mahmoudian… - Nature Reviews …, 2019 - nature.com
The classification and monitoring of individuals with early knee osteoarthritis (OA) are
important considerations for the design and evaluation of therapeutic interventions and …

Update on the role of muscle in the genesis and management of knee osteoarthritis

KL Bennell, TV Wrigley, MA Hunt… - Rheumatic …, 2013 - rheumatic.theclinics.com
The muscles of the lower limb, particularly the quadriceps, play an important role in the
genesis and management of knee osteoarthritis (OA). At the knee, muscles function to …

Knee joint kinematics, kinetics and muscle co-contraction in knee osteoarthritis patient gait

TL Heiden, DG Lloyd, TR Ackland - Clinical biomechanics, 2009 - Elsevier
BACKGROUND: Compared to matched controls, knee osteoarthritis patients walk with
altered, kinematics, kinetics and muscle activity. Studies of osteoarthritis patient gait have …

[HTML][HTML] Knee joint loading during gait in healthy controls and individuals with knee osteoarthritis

D Kumar, KT Manal, KS Rudolph - Osteoarthritis and cartilage, 2013 - Elsevier
OBJECTIVE: People with knee osteoarthritis (OA) are thought to walk with high loads at the
knee which are yet to be quantified using modeling techniques that account for subject …

Biomechanical deviations during level walking associated with knee osteoarthritis: a systematic review and meta‐analysis

K Mills, MA Hunt, R Ferber - Arthritis care & research, 2013 - Wiley Online Library
Objective To identify which gait deviations are consistently associated with knee
osteoarthritis (KOA) and how these are influenced by disease severity, the involved …

Differences in gait parameters between healthy subjects and persons with moderate and severe knee osteoarthritis: a result of altered walking speed?

JA Zeni Jr, JS Higginson - Clinical biomechanics, 2009 - Elsevier
BACKGROUND: While knee osteoarthritis has been shown to affect a multitude of kinematic,
kinetic and temporo-spatial gait parameters, few investigations have examined the effect of …

Knee joint biomechanics in physiological conditions and how pathologies can affect it: a systematic review

L Zhang, G Liu, B Han, Z Wang, Y Yan… - Applied bionics and …, 2020 - Wiley Online Library
The knee joint, as the main lower limb motor joint, is the most vulnerable and susceptible
joint. The knee injuries considerably impact the normal living ability and mental health of …

Sarcopenia: prevalence, mechanisms, and functional consequences

MJ Berger, TJ Doherty - Body composition and aging, 2010 - karger.com
Aging is associated with significant decline in neuromuscular function and performance.
Sarcopenia, often defined as age-related loss of muscle mass, strength, and functional …

Gait analysis as a quantifiable outcome measure in hip or knee osteoarthritis: a systematic review

P Ornetti, JF Maillefert, D Laroche, C Morisset… - Joint Bone Spine, 2010 - Elsevier
OBJECTIVES: Kinematic gait analysis consisting of measuring gait parameters (stride
length, gait speed, dynamic joint angles) is a potential outcome measure in osteoarthritis …

Gait changes in patients with knee osteoarthritis are replicated by experimental knee pain

M Henriksen, T Graven‐Nielsen, J Aaboe… - Arthritis care & …, 2010 - Wiley Online Library
Objective Medial knee osteoarthritis (OA) is characterized by pain and associated with
abnormal knee moments during walking. The relationship between knee OA pain and gait …