Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

In December 2019, the outbreak of the novel coronavirus disease (COVID-19) in China
spread worldwide, becoming an emergency of major international concern. SARS-CoV-2 …

The pandemic outbreak of coronavirus disease 2019 (COVID-19) is rapidly spreading all
over the world. Reports from China showed that about 20% of patients developed severe …

Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

Outbreak and pandemic of coronavirus SARS-CoV-2 in 2019/2020 will challenge global
health for the future. Because a vaccine against the virus will not be available in the near …

Coronaviruses are a large group of viruses known to cause illnesses that vary between the
common cold and more severe diseases to include severe acute respiratory syndrome …

Background Since the outbreak of coronavirus disease 2019 (COVID-19) in China in
December 2019, considerable attention has been focused on its elucidation. However, it is …

COVID-19 has become a global pandemic and there is an urgent call for developing drugs
against the virus (SARS-CoV-2). The 3C-like protease (3CLpro) of SARS-CoV-2 is a …

Background Antiviral therapies against the novel coronavirus SARS-CoV-2, which has
caused a global pandemic of respiratory illness called COVID-19, are still lacking. Methods …

Recent international epidemics of coronavirus-associated illnesses underscore the urgent
medical and public health need for vaccine development and regulatory body approved …