Cellular mechanotransduction: from tension to function
F Martino, AR Perestrelo, V Vinarský, S Pagliari… - Frontiers in …, 2018 - frontiersin.org
Living cells are constantly exposed to mechanical stimuli arising from the surrounding
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …
The cytoskeleton—a complex interacting meshwork
T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
[HTML][HTML] Vimentin on the move: new developments in cell migration
The vimentin gene (VIM) encodes one of the 71 human intermediate filament (IF) proteins,
which are the building blocks of highly ordered, dynamic, and cell type-specific fiber …
which are the building blocks of highly ordered, dynamic, and cell type-specific fiber …
[HTML][HTML] Actin flows mediate a universal coupling between cell speed and cell persistence
Cell movement has essential functions in development, immunity, and cancer. Various cell
migration patterns have been reported, but no general rule has emerged so far. Here, we …
migration patterns have been reported, but no general rule has emerged so far. Here, we …
Cell migration guided by long-lived spatial memory
J d'Alessandro, A Barbier--Chebbah, V Cellerin… - Nature …, 2021 - nature.com
Living cells actively migrate in their environment to perform key biological functions—from
unicellular organisms looking for food to single cells such as fibroblasts, leukocytes or …
unicellular organisms looking for food to single cells such as fibroblasts, leukocytes or …
Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions
Multiple attributes of the three-dimensional (3D) extracellular matrix (ECM) have been
independently implicated as regulators of cell motility, including pore size, crosslink density …
independently implicated as regulators of cell motility, including pore size, crosslink density …
Deposited footprints let cells switch between confined, oscillatory, and exploratory migration
E Perez Ipiña, J d'Alessandro… - Proceedings of the …, 2024 - National Acad Sciences
For eukaryotic cells to heal wounds, respond to immune signals, or metastasize, they must
migrate, often by adhering to extracellular matrix (ECM). Cells may also deposit ECM …
migrate, often by adhering to extracellular matrix (ECM). Cells may also deposit ECM …
Actin flows in cell migration: from locomotion and polarity to trajectories
AC Callan-Jones, R Voituriez - Current opinion in cell biology, 2016 - Elsevier
Eukaryotic cell movement is characterized by very diverse migration modes. Recent studies
show that cells can adapt to environmental cues, such as adhesion and geometric …
show that cells can adapt to environmental cues, such as adhesion and geometric …
The self-organization of plant microtubules inside the cell volume yields their cortical localization, stable alignment, and sensitivity to external cues
Many cell functions rely on the ability of microtubules to self-organize as complex networks.
In plants, cortical microtubules are essential to determine cell shape as they guide the …
In plants, cortical microtubules are essential to determine cell shape as they guide the …
Periodicity, mixed-mode oscillations, and multiple timescales in a phosphoinositide-Rho GTPase network
C San Tong, XJ Xǔ, M Wu - Cell Reports, 2023 - cell.com
While rhythmic contractile behavior is commonly observed at the cellular cortex, the primary
focus has been on excitable or periodic events described by simple activator-delayed …
focus has been on excitable or periodic events described by simple activator-delayed …