Cross-species microarray hybridizations: a developing tool for studying species diversity
The use of cross-species hybridization (CSH) to DNA microarrays, in which the target RNA
and microarray probe are from different species, has increased in the past few years. CSH is …
and microarray probe are from different species, has increased in the past few years. CSH is …
Multiple hypothesis testing in proteomics: a strategy for experimental work
In quantitative proteomics work, the differences in expression of many separate proteins are
routinely examined to test for significant differences between treatments. This leads to the …
routinely examined to test for significant differences between treatments. This leads to the …
Gene expression analysis for the identification of selection and local adaptation in fishes
PF Larsen, PM Schulte, EE Nielsen - Journal of Fish Biology, 2011 - Wiley Online Library
In recent years, variation in gene expression has been recognized as an important
component of environmental adaptation in multiple model species, including a few fish …
component of environmental adaptation in multiple model species, including a few fish …
A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies
Over the last decade, gene expression microarrays have had a profound impact on
biomedical research. The diversity of platforms and analytical methods available to …
biomedical research. The diversity of platforms and analytical methods available to …
Genome-wide expression profiling reveals new insights into pathogenesis and progression of testicular germ cell tumors
K Biermann, LC Heukamp, K Steger… - Cancer genomics & …, 2007 - cgp.iiarjournals.org
Testicular germ cell tumors (GCT) are the most frequent malignancy in young adults and
arise from intratubular germ cell neoplasia undetermined (IGCNU, also referred to as …
arise from intratubular germ cell neoplasia undetermined (IGCNU, also referred to as …
[HTML][HTML] Left ventricular global transcriptional profiling in human end-stage dilated cardiomyopathy
We employed ABI high-density oligonucleotide microarrays containing 31,700 sixty-mer
probes (representing 27,868 annotated human genes) to determine differential gene …
probes (representing 27,868 annotated human genes) to determine differential gene …
Gene expression profiling identifies new biological markers of neoplastic germ cells
K Biermann, LC Heukamp, K Steger, H Zhou… - Anticancer …, 2007 - ar.iiarjournals.org
Background: There is only limited knowledge about gene expression in human testicular
germ cell tumors of adolescents and adults (TGCTs), and, in particular in its pre-invasive …
germ cell tumors of adolescents and adults (TGCTs), and, in particular in its pre-invasive …
Using DNA microarrays to study gene expression in closely related species
Motivation: Comparisons of gene expression levels within and between species have
become a central tool in the study of the genetic basis for phenotypic variation, as well as in …
become a central tool in the study of the genetic basis for phenotypic variation, as well as in …
Modulation of skeletal muscle insulin signaling with chronic caloric restriction in cynomolgus monkeys
ZQ Wang, ZE Floyd, J Qin, X Liu, Y Yu, XH Zhang… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Caloric restriction (CR) has been shown to retard aging processes, extend
maximal life span, and consistently increase insulin action in experimental animals. The …
maximal life span, and consistently increase insulin action in experimental animals. The …
Standardized method for the harvest of nonhuman primate tissue optimized for multiple modes of analyses
AT Davenport, KA Grant, KT Szeliga, DP Friedman… - Cell and tissue …, 2014 - Springer
Appropriate animal models are critical to conduct translational studies of human disorders
without variables that can confound clinical studies. Such analytic methods as patch-clamp …
without variables that can confound clinical studies. Such analytic methods as patch-clamp …