Downstream of the HOX genes: Explaining conflicting tumour suppressor and oncogenic functions in cancer
R Morgan, K Hunter, HS Pandha - International journal of …, 2022 - Wiley Online Library
The HOX genes are a highly conserved group of transcription factors that have key roles in
early development, but which are also highly expressed in most cancers. Many studies have …
early development, but which are also highly expressed in most cancers. Many studies have …
Methylation in HOX Clusters and Its Applications in Cancer Therapy
HOX genes are commonly known for their role in embryonic development, defining the
positional identity of most structures along the anterior–posterior axis. In postembryonic life …
positional identity of most structures along the anterior–posterior axis. In postembryonic life …
[PDF][PDF] RETRACTED: The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis
C Yang, J Zheng, Y Xue, H Yu, X Liu, J Ma… - Frontiers in Molecular …, 2018 - frontiersin.org
Glioblastoma (GBM) is the most aggressive and malignant primary tumor. Angiogenesis
plays a critical role in the progression of GBM. Previous studies have indicated that long non …
plays a critical role in the progression of GBM. Previous studies have indicated that long non …
Long non-coding RNA HOTTIP affects renal cell carcinoma progression by regulating autophagy via the PI3K/Akt/Atg13 signaling pathway
Y Su, J Lu, X Chen, C Liang, P Luo, C Qin… - Journal of cancer …, 2019 - Springer
Objective Renal cell carcinoma (RCC) is the most common malignancy of the urinary
system, and it is a serious threat to human health. HOXA transcript at the distal tip (HOTTIP) …
system, and it is a serious threat to human health. HOXA transcript at the distal tip (HOTTIP) …
[HTML][HTML] Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate HOXA11 expression by sponging miR-181a in multiple myeloma
X Shen, H Bai, H Zhu, Q Yan, Y Yang, W Yu… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Long non-coding RNA maternally expressed gene 3 (MEG3) has been
reported to play an essential role in cancer progression and metastasis. However, the …
reported to play an essential role in cancer progression and metastasis. However, the …
Long Noncoding RNA HOXA11-AS and Transcription Factor HOXB13 Modulate the Expression of Bone Metastasis-Related Genes in Prostate Cancer
A Misawa, Y Kondo, H Takei, T Takizawa - Genes, 2021 - mdpi.com
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression,
which play fundamental roles in cancer development. In this study, we found that homeobox …
which play fundamental roles in cancer development. In this study, we found that homeobox …
Comprehensive analysis of the HOXA gene family identifies HOXA13 as a novel oncogenic gene in kidney renal clear cell carcinoma
Y Cui, M Yan, C Zhang, J Xue, Q Zhang, S Ma… - Journal of Cancer …, 2020 - Springer
Objectives Kidney renal clear cell carcinoma (KIRC) is one of the most common lethal
cancers in the human urogenital system. As members of the Homeobox (HOX) family …
cancers in the human urogenital system. As members of the Homeobox (HOX) family …
Downregulation of HOXA11 enhances endometrial cancer malignancy and cisplatin resistance via activating PTEN/AKT signaling pathway
C Kong, Z Zhu, Y Li, P Xue, L Chen - Clinical and Translational Oncology, 2021 - Springer
Purpose Endometrial cancer is the most common malignant tumor of female genital system
worldwide. Homeobox A11 (HOXA11) is an evolutionarily conserved Homeobox gene …
worldwide. Homeobox A11 (HOXA11) is an evolutionarily conserved Homeobox gene …
[HTML][HTML] Upregulation of HOXA11 during the progression of lung adenocarcinoma detected via multiple approaches
X Yang, Y Deng, RQ He, XJ Li… - International …, 2018 - spandidos-publications.com
The altered expression of homeobox (HOX) A11 has been observed in various malignant
tumor types, but it has remained to be determined in human lung adenocarcinoma (LUAD) …
tumor types, but it has remained to be determined in human lung adenocarcinoma (LUAD) …
An inverse interaction between HOXA11 and HOXA11-AS is associated with cisplatin resistance in lung adenocarcinoma
Y Zhang, Y Yuan, Y Li, P Zhang, P Chen, S Sun - Epigenetics, 2019 - Taylor & Francis
ABSTRACT HOXA11, which is a member of the homeobox (HOX) gene family, and its
natural antisense transcript (NAT) HOXA11-AS have been reported to be closely related to …
natural antisense transcript (NAT) HOXA11-AS have been reported to be closely related to …