In recent years, stem cell therapy has become a very promising and advanced scientific
research topic. The development of treatment methods has evoked great expectations. This …

Periodontal diseases involve injuries to the supporting structures of the tooth and, if left
untreated, can lead to the loss of the tooth. Regenerative periodontal therapies aim, ideally …

Stem cells from human exfoliated deciduous teeth (SHED) have been isolated and
characterized as multipotent cells. However, it is not known whether SHED can generate a …

Odontoblasts produce most of the extracellular matrix (ECM) components found in dentin
and implicated in dentin mineralization. Major differences in the pulp ECM explain why pulp …

OBJECTIVES: Dental tissue disease and trauma provides an excellent model for the
interaction between tissue defence and regenerative processes and has application to many …

Stemming from in vitro and in vivo pre-clinical and human models, tissue-engineering-based
strategies continue to demonstrate great potential for the regeneration of the pulp-dentin …

Caries, pulpitis, and apical periodontitis increase health care costs and attendant loss of
economic productivity. They ultimately result in premature tooth loss and therefore …

Dentin–pulp complex is a term which refers to the dental pulp (DP) surrounded by dentin
along its peripheries. Dentin and dental pulp are highly specialized tissues, which can be …

Stem cells possess multipotent properties that allow them to differentiate into various cells,
which may be potentially useful in tissue regeneration. Stem cell populations are reported to …

As a mineralised connective tissue, dentine is well adapted to its functional role as a major
structural component of the tooth. Although similar in composition to bone, dentine matrix is …