The endoplasmic reticulum (ER) is an intracellular organelle that fosters the correct folding
of linear polypeptides and proteins, a process tightly governed by the ER‐resident enzymes …

The endoplasmic reticulum (ER) acts as a moving organelle with many important cellular
functions. As the ER lacks sufficient nutrients under pathological conditions leading to …

Recent clinical data have suggested a correlation between coronavirus disease 2019
(COVID-19) and diabetes. Here, we describe the detection of SARS-CoV-2 viral antigen in …

Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic β
cells. Individuals with type 1 diabetes are reliant on insulin for survival. Despite enhanced …

Human coronaviruses (HCoVs) are known respiratory pathogens associated with a range of
respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome …

The exposure of hepatocytes to high concentrations of lipids and carbohydrates and the
ensuing hepatocellular injury are termed lipotoxicity and glucotoxicity, respectively. A …

The endoplasmic reticulum (ER) is an essential organelle in eukaryotic cells for the storage
and regulated release of calcium and as the entrance to the secretory pathway. Protein …

Protein-folding stress at the endoplasmic reticulum (ER) is a salient feature of specialized
secretory cells and is also involved in the pathogenesis of many human diseases. ER stress …

Solid tumors often grow in a micro-environment characterized by< 2% O 2 tension. This
condition, together with the aberrant activation of specific oncogenic patwhays, increases …

The endoplasmic reticulum (ER) is a dynamic intracellular organelle with multiple functions
essential for cellular homeostasis, development, and stress responsiveness. In response to …