A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry

RS Keri, MR Patil, SA Patil, S Budagumpi - European Journal of Medicinal …, 2015 - Elsevier
Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …

Benzimidazole: A milestone in the field of medicinal chemistry

MS Vasava, MN Bhoi, SK Rathwa… - Mini reviews in …, 2020 - ingentaconnect.com
In the last 2-3 decades, the broad research in the application of benzimidazole derivatives
made it important for mankind. Many scientists have worked on benzimidazole derivatives …

[HTML][HTML] Diosgenin from Dioscorea bulbifera: Novel Hit for Treatment of Type II Diabetes Mellitus with Inhibitory Activity against α-Amylase and α-Glucosidase

S Ghosh, P More, A Derle, AB Patil, P Markad, A Asok… - PloS one, 2014 - journals.plos.org
Diabetes mellitus is a multifactorial metabolic disease characterized by post-prandial
hyperglycemia (PPHG). α-amylase and α-glucosidase inhibitors aim to explore novel …

Recent advances in the chemistry and biology of benzothiazoles

RK Gill, RK Rawal, J Bariwal - Archiv der Pharmazie, 2015 - Wiley Online Library
Benzothiazole is a privileged heterocyclic scaffold having a benzene ring fused with a five‐
membered thiazole ring. This moiety has attracted considerable attention because of its …

An insight of alpha-amylase inhibitors as a valuable tool in the management of type 2 diabetes mellitus

R Bashary, M Vyas, SK Nayak, A Suttee… - Current diabetes …, 2020 - ingentaconnect.com
Background: Among the millions of people around the world, the most prevalent metabolic
disorder is diabetes mellitus. Due to the drawbacks which are associated with commercially …

[PDF][PDF] Antidiabetic and antioxidant properties of copper nanoparticles synthesized by medicinal plant Dioscorea bulbifera

S Ghosh, P More, R Nitnavare, S Jagtap… - … of Nanomedicine & …, 2015 - researchgate.net
Background: Biological route for synthesis of copper nanoparticles (CuNPs) with therapeutic
potential is a major challenge. In this study, CuNPs were synthesized by D. bulbifera tuber …

Chemistry of Ketene N,S-Acetals: An Overview

L Zhang, J Dong, X Xu, Q Liu - Chemical Reviews, 2016 - ACS Publications
Push–pull alkenes, which bear electron-donating and-accepting group (s) at both termini of
a C C double bond, respectively, are of interest not only for their unique electronic …

Exploring biological efficacy of novel benzothiazole linked 2, 5-disubstituted-1, 3, 4-oxadiazole hybrids as efficient α-amylase inhibitors: Synthesis, characterization …

M Duhan, P Kumar, J Sindhu, R Singh, M Devi… - Computers in Biology …, 2021 - Elsevier
In an effort to explore a class of novel antidiabetic agents, we have made an effort to
synergize the α-amylase inhibitory potential of 1, 3-benzothiazole and 1, 3, 4-oxadiazole …

[HTML][HTML] Importance of fluorine in benzazole compounds

T Al-Harthy, W Zoghaib, R Abdel-Jalil - Molecules, 2020 - mdpi.com
Fluorine-containing heterocycles continue to receive considerable attention due to their
unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules …

Biological aspects of emerging benzothiazoles: a short review

R Ali, N Siddiqui - Journal of chemistry, 2013 - Wiley Online Library
In recent years heterocyclic compounds analogues and derivatives have attracted wide
attention due to their useful biological and pharmacological properties. Benzothiazole is …