Matrix‐free methods for laser desorption/ionization mass spectrometry

DS Peterson - Mass spectrometry reviews, 2007 - Wiley Online Library
Matrix assisted laser desorption/ionization (MALDI) is a soft ionization mass spectrometric
method that has become a preeminent technique in the analysis of a wide variety of …

Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review

HN Abdelhamid - Microchimica Acta, 2019 - Springer
Great endeavors are undertaken to find effective nanoparticles to replace organic matrices
for the analysis of small molecules using laser desorption ionization mass spectrometry (LDI …

Carbon nanotubes as assisted matrix for laser desorption/ionization time-of-flight mass spectrometry

S Xu, Y Li, H Zou, J Qiu, Z Guo, B Guo - Analytical chemistry, 2003 - ACS Publications
Analysis of low molecular weight compounds with matrix-assisted laser
desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) has been developed …

Direct analysis of drug candidates in tissue by matrix‐assisted laser desorption/ionization mass spectrometry

ML Reyzer, Y Hsieh, K Ng… - Journal of Mass …, 2003 - Wiley Online Library
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) has been used
to directly analyze and image pharmaceutical compounds in intact tissue. The anti‐tumor …

Nanoparticle assisted laser desorption/ionization mass spectrometry for small molecule analytes

HN Abdelhamid - Microchimica Acta, 2018 - Springer
Nanoparticle assisted laser desorption/ionization mass spectrometry (NPs-ALDI-MS) shows
remarkable characteristics and has a promising future in terms of real sample analysis. The …

Desorption/ionization on silicon nanowires

EP Go, JV Apon, G Luo, A Saghatelian… - Analytical …, 2005 - ACS Publications
Dense arrays of single-crystal silicon nanowires (SiNWs) have been used as a platform for
laser desorption/ionization mass spectrometry of small molecules, peptides, protein digests …

A method for the analysis of low-mass molecules by MALDI-TOF mass spectrometry

Z Guo, Q Zhang, H Zou, B Guo, J Ni - Analytical chemistry, 2002 - ACS Publications
We report a novel method termed matrix suppressed laser desorption/ionization to improve
the analysis of low-mass molecules by MALDI-TOF mass spectrometry. In this method, the …

Ion desorption efficiency and internal energy transfer in carbon-based surface-assisted laser desorption/ionization mass spectrometry: desorption mechanism (s) and …

HW Tang, KM Ng, W Lu, CM Che - Analytical chemistry, 2009 - ACS Publications
Ion desorption efficiency and internal energy transfer were probed and correlated in carbon-
based surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) using …

Desorption/ionization on silicon (DIOS) mass spectrometry: background and applications

WG Lewis, Z Shen, MG Finn, G Siuzdak - International Journal of Mass …, 2003 - Elsevier
Desorption/ionization on silicon mass spectrometry (DIOS-MS) is a matrix-less laser
vaporization method for generating gas-phase ions. The physical properties of the silicon …

Gold nanoparticle-enhanced target (AuNPET) as universal solution for laser desorption/ionization mass spectrometry analysis and imaging of low molecular weight …

J Sekuła, J Nizioł, W Rode, T Ruman - Analytica Chimica Acta, 2015 - Elsevier
Preparation is described of a durable surface of cationic gold nanoparticles (AuNPs),
covering commercial and custom-made MALDI targets, along with characterization of the …