Signaling by exosomal microRNAs in cancer
A class of small non-coding RNAs, the microRNAs (miRNAs), have recently attracted great
attention in cancer research since they play a central role in regulation of gene-expression …
attention in cancer research since they play a central role in regulation of gene-expression …
Neuroblastoma treatment in the post-genomic era
Neuroblastoma is an embryonic malignancy of early childhood originating from neural crest
cells and showing heterogeneous biological, morphological, genetic and clinical …
cells and showing heterogeneous biological, morphological, genetic and clinical …
Mutational dynamics between primary and relapse neuroblastomas
Neuroblastoma is a malignancy of the developing sympathetic nervous system that is often
lethal when relapse occurs. We here used whole-exome sequencing, mRNA expression …
lethal when relapse occurs. We here used whole-exome sequencing, mRNA expression …
Hyaluronic acid-coated PEI-PLGA nanoparticles mediated co-delivery of doxorubicin and miR-542-3p for triple negative breast cancer therapy
MicroRNAs (miRNAs) play critical roles in modulating the oncogenic driver pathways
involved in the acquisition of resistance to cancer treatments. MiR-542-3p serves as a potent …
involved in the acquisition of resistance to cancer treatments. MiR-542-3p serves as a potent …
Nanotechnological based miRNA intervention in the therapeutic management of neuroblastoma
Neuroblastoma (NB) is a widely diagnosed cancer in children, characterized by
amplification of the gene encoding the MYCN transcription factor, which is highly predictive …
amplification of the gene encoding the MYCN transcription factor, which is highly predictive …
Smart nanomaterials for cancer diagnosis and treatment
Innovations in nanomedicine has guided the improved outcomes for cancer diagnosis and
therapy. However, frequent use of nanomaterials remains challenging due to specific …
therapy. However, frequent use of nanomaterials remains challenging due to specific …
miR-15a and miR-15b modulate natural killer and CD8+ T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma
AS Pathania, P Prathipati, OA Olwenyi, S Chava… - Molecular Therapy …, 2022 - cell.com
Neuroblastoma (NB) is an enigmatic and deadliest pediatric cancer to treat. The major
obstacles to the effective immunotherapy treatments in NB are defective immune cells and …
obstacles to the effective immunotherapy treatments in NB are defective immune cells and …
A focus on regulatory networks linking MicroRNAs, transcription factors and target genes in neuroblastoma
P Perri, M Ponzoni, MV Corrias, I Ceccherini… - Cancers, 2021 - mdpi.com
Simple Summary Neuroblastoma is a tumor of the sympathetic nervous system that
substantially contributes to childhood cancer mortality. Neuroblastoma originates from the …
substantially contributes to childhood cancer mortality. Neuroblastoma originates from the …
Nanomaterial–microbe cross-talk: physicochemical principles and (patho) biological consequences
D Westmeier, A Hahlbrock, C Reinhardt… - Chemical Society …, 2018 - pubs.rsc.org
The applications of nanoparticles (NPs) are increasing exponentially in consumer products,
biotechnology and biomedicine, and humans, as well as the environment, are increasingly …
biotechnology and biomedicine, and humans, as well as the environment, are increasingly …
Targeting the apoptosis pathway to treat tumours of the paediatric nervous system
MC Fitzgerald, PJ O'Halloran, NMC Connolly… - Cell Death & …, 2022 - nature.com
New, more effective therapeutics are required for the treatment of paediatric cancers.
Current treatment protocols of cytotoxic treatments including chemotherapy trigger cancer …
Current treatment protocols of cytotoxic treatments including chemotherapy trigger cancer …