In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Solid-state nuclear magnetic resonance (NMR) spectroscopy is an atomic-level method to
determine the chemical structure, 3D structure and dynamics of solids and semi-solids. This …

The ubiquitous heat shock protein 70 (HSP70) family consists of ATP-dependent molecular
chaperones, which perform numerous cellular functions that affect almost all aspects of the …

Much of postgenomic biochemistry and all of structural biology are based on the premise
that the starting point for both understanding specific biochemical processes, such as affinity …

NMR spectroscopy is one of the most important methods for determining protein structures.
The scientific community is constantly pushing the limits of NMR spectroscopy by …

Nuclear magnetic resonance (NMR) spectroscopy is now established as the method of
choice for the study of the structure and dynamics of proteins and nucleic acids in solution …

The three-dimensional structure of the channel-forming trans-membrane domain of virus
protein “u”(Vpu) of HIV-1 was determined by NMR spectroscopy in micelle and bilayer …

Amantadine is known to block the M2 proton channel of the Influenza A virus. Here, we
present a structure of the M2 trans-membrane domain blocked with amantadine, built using …

J-domain chaperones are involved in the efficient handover of misfolded/partially folded
proteins to Hsp70 but also function independently to protect against cell death. Due to their …

Gone are the days when solid-state NMR spectroscopy was considered to be untouchable-
like as it provided unappealing spectral lines due to poor resolution and sensitivity …