Methods and protocols for prediction of immunogenic epitopes
JC Tong, TW Tan, S Ranganathan - Briefings in Bioinformatics, 2007 - academic.oup.com
T-cell recognition of peptide/major histocompatibility complex (MHC) is a prerequisite for
cellular immunity. Recently, there has been an influx of bioinformatics tools to facilitate the …
cellular immunity. Recently, there has been an influx of bioinformatics tools to facilitate the …
Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method
Abstract Background Antigen presenting cells (APCs) sample the extra cellular space and
present peptides from here to T helper cells, which can be activated if the peptides are of …
present peptides from here to T helper cells, which can be activated if the peptides are of …
Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries
Background It has been previously shown that combinatorial peptide libraries are a useful
tool to characterize the binding specificity of class I MHC molecules. Compared to other …
tool to characterize the binding specificity of class I MHC molecules. Compared to other …
CD4+ T Cell Epitope Discovery and Rational Vaccine Design
T cell epitope-driven vaccine design employs bioinformatic algorithms to identify potential
targets of vaccines against infectious diseases or cancer. Potential epitopes can be …
targets of vaccines against infectious diseases or cancer. Potential epitopes can be …
A community resource benchmarking predictions of peptide binding to MHC-I molecules
Recognition of peptides bound to major histocompatibility complex (MHC) class I molecules
by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a …
by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a …
Two MP2CL5 antigen vaccines from Naegleria fowleri stimulate the immune response against meningitis in the BALB/c model
M Gutiérrez-Sánchez, MM Carrasco-Yépez… - Infection and …, 2023 - Am Soc Microbiol
Naegleria fowleri is an etiological agent that generates primary amoebic
meningoencephalitis; unfortunately, no effective treatment or vaccine is available. The …
meningoencephalitis; unfortunately, no effective treatment or vaccine is available. The …
Multiple T cell epitope peptides suppress allergic responses in an egg allergy mouse model by the elicitation of forkhead box transcription factor 3‐and transforming …
Background Peptide‐based immunotherapy (PIT) represents an attractive approach for
targeted interventions in immunological disorders, but has not been widely explored in the …
targeted interventions in immunological disorders, but has not been widely explored in the …
An immunoproteomic approach revealing peptides from Sporothrix brasiliensis that induce a cellular immune response in subcutaneous sporotrichosis
Sporothrix brasiliensis is the most virulent fungus of the Sporothrix complex and is the main
species recovered in the sporotrichosis zoonotic hyperendemic area in Rio de Janeiro. A …
species recovered in the sporotrichosis zoonotic hyperendemic area in Rio de Janeiro. A …
Current research into novel therapeutic vaccines against cervical cancer
MN Cordeiro, RCP De Lima, F Paolini… - Expert Review of …, 2018 - Taylor & Francis
Introduction: Cervical cancer and cervical intraepithelial neoplasia (CIN) are well-known
outcomes of a human papillomavirus (HPV) infection. Viral oncogenes expressions like E6 …
outcomes of a human papillomavirus (HPV) infection. Viral oncogenes expressions like E6 …
Vaccine design and vaccination strategies against rickettsiae
A Osterloh - Vaccines, 2021 - mdpi.com
Rickettsioses are febrile, potentially lethal infectious diseases that are a serious health
threat, especially in poor income countries. The causative agents are small obligate …
threat, especially in poor income countries. The causative agents are small obligate …