The impact of low-protein high-carbohydrate diets on aging and lifespan
Most research on nutritional effects on aging has focussed on the impact of manipulating
single dietary factors such as total calorie intake or each of the macronutrients individually …
single dietary factors such as total calorie intake or each of the macronutrients individually …
[HTML][HTML] Macronutrients and caloric intake in health and longevity
Both lifespan and healthspan are influenced by nutrition, with nutritional interventions
proving to be robust across a wide range of species. However, the relationship between …
proving to be robust across a wide range of species. However, the relationship between …
Dietary protein to carbohydrate ratio and caloric restriction: comparing metabolic outcomes in mice
Both caloric restriction (CR) and low-protein, high-carbohydrate (LPHC) ad-libitum-fed diets
increase lifespan and improve metabolic parameters such as insulin, glucose, and blood …
increase lifespan and improve metabolic parameters such as insulin, glucose, and blood …
Diet-microbiome interactions in health are controlled by intestinal nitrogen source constraints
AJ Holmes, YV Chew, F Colakoglu, JB Cliff… - Cell Metabolism, 2017 - cell.com
Diet influences health and patterns of disease in populations. How different diets do this and
why outcomes of diets vary between individuals are complex and involve interaction with the …
why outcomes of diets vary between individuals are complex and involve interaction with the …
Microbial nitrogen limitation in the mammalian large intestine
Resource limitation is a fundamental factor governing the composition and function of
ecological communities. However, the role of resource supply in structuring the intestinal …
ecological communities. However, the role of resource supply in structuring the intestinal …
Putting the balance back in diet
The notion of dietary balance is fundamental to health yet is not captured by focusing on the
intake of energy or single nutrients. Advances in nutritional geometry have begun to unravel …
intake of energy or single nutrients. Advances in nutritional geometry have begun to unravel …
Defining the nutritional and metabolic context of FGF21 using the geometric framework
Summary Fibroblast growth factor 21 (FGF21) is the first known endocrine signal activated
by protein restriction. Although FGF21 is robustly elevated in low-protein environments …
by protein restriction. Although FGF21 is robustly elevated in low-protein environments …
Nutritional strategies to optimise cognitive function in the aging brain
Old age is the greatest risk factor for most neurodegenerative diseases. During recent
decades there have been major advances in understanding the biology of aging, and the …
decades there have been major advances in understanding the biology of aging, and the …
Do wild carnivores forage for prey or for nutrients? Evidence for nutrient‐specific foraging in vertebrate predators
A widespread perception is that carnivores are limited by the amount of prey that can be
captured rather than their nutritional quality, and thus have no need to regulate …
captured rather than their nutritional quality, and thus have no need to regulate …
[HTML][HTML] Diet modulates the relationship between immune gene expression and functional immune responses
SC Cotter, CE Reavey, Y Tummala, JL Randall… - Insect biochemistry and …, 2019 - Elsevier
Nutrition is vital to health and the availability of resources has long been acknowledged as a
key factor in the ability to fight off parasites, as investing in the immune system is costly …
key factor in the ability to fight off parasites, as investing in the immune system is costly …