Broad-spectrum antiviral properties of andrographolide

S Gupta, KP Mishra, L Ganju - Archives of virology, 2017 - Springer
Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated
from various plants of the genus Andrographis, commonly known as 'creat'. This purified …

The role of cytokines in hepatocellular carcinoma

A Budhu, XW Wang - Journal of leukocyte biology, 2006 - academic.oup.com
Hepatocellular carcinoma (HCC) is a frequent malignancy worldwide with a high rate of
metastasis. The hepatitis B and C viruses are considered major etiological factors …

HIV and co‐infections

CC Chang, M Crane, JL Zhou, M Mina… - Immunological …, 2013 - Wiley Online Library
Despite significant reductions in morbidity and mortality secondary to availability of effective
combination anti‐retroviral therapy (cART), human immunodeficiency virus (HIV) infection …

The tumor microenvironment in hepatocellular carcinoma

GC Leonardi, S Candido… - International …, 2012 - spandidos-publications.com
The tumor microenvironment has been largely studied as a dynamic system orchestrated by
inflammatory cells, including cancer cells, stroma as well as the extracellular matrix. It is …

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C

K Thabet, A Asimakopoulos, M Shojaei… - Nature …, 2016 - nature.com
Cirrhosis likely shares common pathophysiological pathways despite arising from a variety
of liver diseases. A recent GWAS identified rs641738, a polymorphism in the MBOAT7 locus …

Harmful effects and potential benefits of anti-tumor necrosis factor (TNF)-α on the liver

LR Lopetuso, G Mocci, M Marzo, F D'Aversa… - International journal of …, 2018 - mdpi.com
Anti-tumor necrosis factor (TNF)-α agents represent an effective treatment for chronic
inflammatory diseases. However, some concerns about their potentially undesirable effects …

Managing occupational risks for hepatitis C transmission in the health care setting

DK Henderson - Clinical microbiology reviews, 2003 - Am Soc Microbiol
Hepatitis C virus (HCV) infection is a significant contemporary health problem in the United
States and elsewhere. Because it is primarily transmitted via blood, hepatitis C infection …

Hepatitis B and C virus infections and anti‐tumor necrosis factor‐α therapy: Guidelines for clinical approach

DM Nathan, PW Angus… - Journal of gastroenterology …, 2006 - Wiley Online Library
Anti‐tumor necrosis factor‐α (TNF) therapy has recently been recognized to be associated
with activation of hepatitis B virus (HBV) infection, with a potentially fatal outcome, mirroring …

Frequent recovery and broad genotype 2 diversity characterize hepatitis C virus infection in Ghana, West Africa

D Candotti, J Temple, F Sarkodie, JP Allain - Journal of virology, 2003 - Am Soc Microbiol
Hepatitis C virus (HCV) infection is thought to mostly become chronic and rarely resolves.
HCV infection was serologically screened in 4,984 samples from Ghanaian blood donors …

Clearance of hepatitis C viremia associated with cellular immunity in the absence of seroconversion in the hepatitis C incidence and transmission in prisons study …

JJ Post, Y Pan, AJ Freeman, CE Harvey… - Journal of Infectious …, 2004 - academic.oup.com
Understanding the earliest virological and immunological events in acute hepatitis C virus
(HCV) infection may provide insight into the determinants of protective immunity. Four cases …